Low-dose oral methotrexate treatment in chronic progressive multiple sclerosis

Neurological Sciences

Volumn 22, Issue 2, 2001, Pages 209-210

  Lugaresi, A ^a   Caporale, C ^a   Farina, D ^a   Marzoli, F ^a   Bonanni, L ^a   Muraro, P A ^a   De Luca, G ^a   Larlori, C ^a   Gambi, D ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Interferon; Methotrexate; Multiple sclerosis; Review

Indexed keywords

METHOTREXATE;

ANTIINFLAMMATORY ACTIVITY; CLINICAL ARTICLE; CONFERENCE PAPER; DISEASE COURSE; DOSE RESPONSE; DRUG SAFETY; ENZYME ASSAY; FOLLOW UP; HERPES ZOSTER; HUMAN; IMMUNOMODULATION; LIVER TOXICITY; LONG TERM CARE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; SCHOOL CHILD; SIDE EFFECT;

ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MAGNETIC RESONANCE IMAGING; METHOTREXATE; MIDDLE AGED; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; TREATMENT OUTCOME;

EID: 0034791382     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100720170026     Document Type: Conference Paper

References (5)

1. Goodkin D, Fischer JS (1996) Treatment of multiple sclerosis with methotrexate. In: Goodkin D, Rudick R (eds) Multiple sclerosis. Advances in clinical trial design, treatment and future perspectives. Springer, Berlin Heidelberg New York, pp 250-287
2. Currier R, Haerer A, Meydrech E (1993) Low dose oral methotrexate treatment of multiple sclerosis: a pilot study. J Neural Neurosurg Psychiatry 56:1217-1218
3. Goodkin E, Rudick R, VanderBrug Medendorp S et al (1995) Low-dose (7.5 mg) oral methotrexate reduces the rate of progression in chronic progressive multiple sclerosis. Ann Neurol 37:30-40
4. Goodkin D, Rudick R, VanderBrug Medendorp S et al (1996) Low-dose oral methotrexate in chronic progressive multiple sclerosis: analyses of serial MRIs. Neurology 47:1153-1157
5. Whartenby K, Mills P, Rogg J et al (2000) An open label trial of combination MS therapy using IFNbla ("AVONEX") and oral methotrexate 20 mg weekly. Neurology AAN, San Diego (abstract)