Characteristics of APC gene mutations in colorectal tumors

Chinese Journal of Medical Genetics

Volumn 18, Issue 5, 2001, Pages 351-355

  Huang, J ^a   Zheng, S ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Adenomatous polyposis coli gene; Colorectal tumor; Mutation

Indexed keywords

BIOASSAY; GENES; SPECTRUM ANALYSIS; TUMORS;

MUTATIONS;

GENETIC ENGINEERING;

APC PROTEIN;

ADULT; ALLELE; ARTICLE; BASE MISPAIRING; COLON POLYPOSIS; COLORECTAL CANCER; COLORECTAL TUMOR; CONTROLLED STUDY; CPG ISLAND; DELETION MUTANT; DNA REPAIR; FEMALE; FRAMESHIFT MUTATION; GENE INSERTION; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; POINT MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SOMATIC MUTATION;

COLORECTAL NEOPLASMS; GENES, APC; HUMANS; MUTATION;

EID: 0034786960     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. APC mutations occur early during colorectal tumorigenesis
2. Molecular determinants of dysplasia in colorectal lesions
3. Molecular diagnosis of familial adenomatous polyposis
4. Rapid detection of translation-termination mutations at the APC gene by direct protein test
5. Identification of mismatch repair genes and their role in the development of cancer
6. Increased mutation rate at the HPRT locus accompanies microsatellite instability in colon cancer
7. Genetic alteration in rat colon tumors induced by heterocyclic amines
8. Characterization of the APC gene in sporadic gastric adenocarcinoma
9. Somatic mutation of the APC gene in sporadic hepatoblastomas
10. APC gene mutation in human prostate cancer