Effect of the pseudorabies virus US3 protein on nuclear membrane localization of the UL34 protein and virus egress from the nucleus

Journal of General Virology

Volumn 82, Issue 10, 2001, Pages 2363-2371

  Klupp, B G ^a   Granzow, H ^a   Mettenleiter, T C ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN B; PROTEIN C; PROTEIN KINASE; UL34 PROTEIN; UNCLASSIFIED DRUG; US3 KINASE; US3 PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DELETION MUTANT; GENETIC CODE; HERPES SIMPLEX VIRUS 1; HERPES VIRUS; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PSEUDORABIES HERPETOVIRUS; ULTRASTRUCTURE; VIRION; VIRUS CAPSID; VIRUS ENVELOPE; VIRUS ISOLATION; VIRUS MORPHOGENESIS;

EID: 0034784870     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-10-2363     Document Type: Article

References (22)

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8. A comparison of herpes simplex and pseudorabies viruses
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10. Pseudorabies virus glycoprotein gK is a virion structural component involved in virus release but is not required for entry
11. Primary envelopment of pseudorabies virus at the nuclear membrane requires the UL34 gene product
12. Demonstration of three major species of pseudorabies virus glycoproteins and identification of a disulfide-linked glycoprotein complex
13. Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration, but only gII is involved in membrane fusion
14. The substrate specificity of the protein kinase induced in cells infected with herpesviruses: Studies with synthetic substrates indicate structural requirements distinct from other protein kinases
15. Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture
16. The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates post-translational modification of the phosphoprotein encoded by the UL34 gene
17. UL34, the target of the herpes simplex US3 protein kinase, is a membrane protein which in its unphosphorylated state associates with novel phosphoproteins
18. Herpes simplex virus type 1 UL34 gene product is required for viral envelopment
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20. The US3-encoded protein kinase from pseudorabies virus affects egress of virions from the nucleus
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22. The protein kinase encoded in the short unique region of pseudorabies virus: Description of the gene and identification of its product in virions and in infected cells