Synthesis, isolation and characterization of Plasmodium falciparum antigenic tetrabranched peptide dendrimers obtained by thiazolidine linkages

Journal of Peptide Research

Volumn 58, Issue 4, 2001, Pages 307-316

  Chaves, Francisco ^a   Calvo, J C ^a   Carvajal, C ^a   Rivera, Z ^a   Ramirez L ^a   Pinto, M ^a   Trujillo, M ^a   Guzman F ^a   Patarroyo, Manuel Elkin ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Dendrimer; Peptide; Tetrabranched; Thiazolidine

Indexed keywords

APICAL MEROZOITE ANTIGEN PROTEIN 1; DENDRIMER; HALIDE; HYDRAZONE DERIVATIVE; MALARIA VACCINE; OXIME; POLYPEPTIDE; THIAZOLIDINE DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DRUG BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOGENICITY; MOLECULAR WEIGHT; NONHUMAN; PEPTIDE SYNTHESIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ISOLATION; RABBIT; REACTION ANALYSIS; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ALDEHYDES; ALKALIES; ANIMALS; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; DENDRITIC CELLS; HYDRAZONES; IMMUNE SERA; PEPTIDES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RABBITS; RECOMBINANT PROTEINS; THIAZOLES; VACCINES;

ANIMALIA; ORYCTOLAGUS CUNICULUS; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0034781645     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2001.00921.x     Document Type: Article

References (18)

1. A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria
2. Immunological evaluation of multiple antigen peptide (MAP) system using the major immunogenic site of foot-and-mouth disease virus
3. Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigen peptide system
4. Vaccine engineering: Enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes
5. Protection of cattle against foot-and-mouth disease by a synthetic peptide
6. Facile synthesis of homogeneous artificial proteins
7. Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages
8. Protein conjugates of defined structure: Synthesis and use of a new carrier molecule
9. Direct synthesis and characterisation of multi-dendritic peptides for use as immunogens
10. Preparation of well-defined protein conjugates using enzyme assisted reverse proteolysis
11. Unprotected peptides as building blocks for branched peptides and peptide dendrimers
12. Chemically unambiguous peptide immunogen: Preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system
13. A new synthetic functionalised antigen carrier
14. Continuous culture of Plasmodium falciparum: Its impact on malaria research
15. Study of the safety and immunogenicity of the synthetic malaria SPf66 vaccine in children aged 1-14 years
16. The first field trials of the chemically synthesised malaria vaccine SPf66. Safety immunogenicity and protectivity
17. SPf66, a chemically synthesised subunit malaria vaccine is safe and immunogenic in Tanzania exposed to intense malaria transmission
18. Plasmodium falciparum AMA-1 erythrocyte binding peptides implicate AMA-1 as erythrocyte binding protein