Lung injury in neonates: Causes, strategies for prevention, and long-term consequences

Journal of Pediatrics

Volumn 139, Issue 4, 2001, Pages 478-486

  Clark, Reese H ^a,b,c,d,e,f   Gerstmann, Dale R ^a,b,c,d,e,f   Jobe, Alan H ^a,b,c,d,e,f   Moffitt, Stephen T ^a,b,c,d,e,f   Slutsky, Arthur S ^a,b,c,d,e,f   Yoder, Bradley A ^a,b,c,d,e,f  

^a PEDIATRIX MEDICAL GROUP   (United States)

^b UTAH VALLEY REGIONAL MEDICAL CENTER   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d Capital Health System   (United States)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; CYTOKINE; DNA; FREE RADICAL; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPID; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SURFACTANT; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE B2; TUMOR NECROSIS FACTOR ALPHA;

AIRWAY PRESSURE; ARTERIAL CARBON DIOXIDE TENSION; ARTIFICIAL VENTILATION; ATELECTASIS; CLINICAL TRIAL; FUNCTIONAL RESIDUAL CAPACITY; HIGH FREQUENCY VENTILATION; HUMAN; HYALINE MEMBRANE DISEASE; LUNG DEVELOPMENT; LUNG DYSPLASIA; LUNG INJURY; LUNG VOLUME; NONHUMAN; OXYGEN SATURATION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATORY DISTRESS; REVIEW; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THORAX RADIOGRAPHY;

EID: 0034781588     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/mpd.2001.118201     Document Type: Article

References (84)

1. Do clinical markers of barotrauma and oxygen toxicity explain interhospital variation in rates of chronic lung disease?
2. Early prediction of neonatal chronic lung disease: A comparison of three scoring methods
3. Bronchopulmonary dysplasia: Correlation of radiographic and clinical findings
4. Positive end-expiratory pressure preserves surfactant function in preterm lambs
5. Rescue high frequency oscillatory ventilation versus conventional ventilation for pulmonary dysfunction in preterm infants
6. Effects of minimal ventilation in a multicenter randomized controlled trial of ventilator support and early corticosteroid therapy in extremely low birth weight infants
7. Mechanisms initiating lung injury in the preterm
8. Lung injury caused by mechanical ventilation
9. Ventilator-induced injury: From barotrauma to biotrauma
10. Tidal ventilation at low airway pressures can augment lung injury
11. Comparison of conventional and high-frequency ventilation: Oxygenation and lung pathology
12. Oxygenation during high-frequency ventilation compared with conventional mechanical ventilation in two models of lung injury
13. Role of tidal volume, FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation
14. Role of lung volume in lung injury: HFO in the atelectasisprone lung
15. Optimizing alveolar expansion prolongs the effectiveness of exogenous surfactant therapy in the adult rabbit
16. Role of lung injury in the pathogenesis of hyaline membrane disease in premature baboons
17. High-frequency oscillatory ventilation versus intermittent mandatory ventilation: Early hemodynamic effects in the premature baboon with hyaline membrane disease
18. Tidal volume effects on surfactant treatment responses with the initiation of ventilation in preterm lambs
19. Independent and combined effects of inhaled nitric oxide, liquid perfluorochemical, and high-frequency oscillatory ventilation in premature lambs with respiratory distress syndrome
20. Barotrauma is volutrauma, but which volume is the one responsible?
21. Ventilator-induced lung injury: Lessons from experimental studies
22. Mechanisms of ventilator-induced lung injury
23. Multiple system organ failure. Is mechanical ventilation a contributing factor?
24. Manual ventilation with a few large breaths at birth compromises the therapeutic effect of subsequent surfactant replacement in immature lambs
25. Antioxidants, nutrition, and bronchopulmonary dysplasia
26. Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome
27. High frequency oscillation
28. Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung
29. Intraalveolar expression of tumor necrosis factor-alpha gene during conventional and high-frequency ventilation
30. Hyperventilation induces release of cytokines from perfused mouse lung
31. Effect of mechanical ventilation strategy on dissemination of intratracheally instilled Escherichia coli in dogs
32. Adverse ventilatory strategy causes pulmonary-to-systemic translocation of endotoxin
33. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial
34. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome
35. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
36. Lung volume recruitment in lambs during high-frequency oscillatory ventilation using respiratory inductive plethysmography
37. Understanding the pressure cost of ventilation: Why does high-frequency ventilation work?
38. Prognosis with preoperative pulmonary function and lung volume assessment in infants with congenital diaphragmatic hernia
39. Detecting lung overdistention in newhorns treated with high-frequency oscillatory ventilation
40. Early nasal continuous positive airway pressure treatment reduces the need for intubation in very low birth weight infants
41. A comparison of underwater bubble continuous positive airway pressure with ventilator-derived continuous positive airway pressure in premature neonates ready for extubation
42. Surfactant and acute lung injury
43. Effect of volume recruitment on response to surfactant treatment in rabbits with lung injury
44. Comparison of infasurf (calf lung surfactant extract) to survanta (Beractant) in the treatment and prevention of respiratory distress syndrome
45. Observational evidence for the efficacy of antenatal steroids from randomized studies of surfactant replacement
46. A multicenter randomized masked comparison trial of synthetic surfactant versus calf lung surfactant extract in the prevention of neonatal respiratory distress syndrome
47. Pulmonary surfactant therapy
48. Synthetic surfactant
49. Surfactant replacement therapy improves ventilation inhomogeneity in infants with respiratory distress syndrome
50. Schoo-age follow-up of prophylactic versus rescue surfactant trial: Pulmonary, neurodevelopmental, and educational outcomes
51. High-frequency oscillatory ventilation for adult respiratory distress syndrome: Let's get it right this time!
52. Pulmonary interstitial emphysema in the premature baboon with hyaline membrane disease
53. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants
54. High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants
55. A prospective, randomized, multicenter trial of high-frequency oscillatory ventilation compared with conventional ventilation in preterm infants with respiratory distress syndrome receiving surfactant
56. Prospective randomized comparison of high-frequency oscillatory and conventional ventilation in respiratory distress syndrome
57. The provo multicenter early high-frequency oscillatory ventilation trial: Improved pulmonary and clinical outcome in respiratory distress syndrome
58. A multicenter randomized trial of high frequency oscillatory ventilation as compared with conventional mechanical ventilation in preterm infants with respiratory failure
59. Randomized comparison of high-frequency ventilation with high-rate intermittent positive pressure ventilation in preterm infants with respiratory failure
60. Controversies in high-frequency ventilation
61. Multicenter controlled clinical trial of high-frequency jet ventilation in preterm infants with uncomplicated respiratory distress syndrome
62. High-frequency jet ventilation in the early management of respiratory distress syndrome is associated with a greater risk for adverse outcomes
63. Effects of hypocarbia on the development of cystic periventricular leukomalacia in premature infants treated with high-frequency jet ventilation
64. Carbon dioxide protects the perinatal brain from hypoxicischemic damage: An experimental study in the immature rat
65. Buffering hypercapnic acidosis worsens acute lung injury
66. Metabolic acidosis-induced retinopathy in the neonatal rat
67. Carbon dioxide-induced retinopathy in the neonatal rat
68. Supplemental Therapeutic Oxygen for Prethreshold Retinopathy Of Prematurity (STOP-ROP), a randomized, controlled trial. 1: Primary outcomes
69. Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation
70. Safety and pharmacokinetics of multiple doses of recombinant human CuZn superoxide dismutase administered intratracheally to premature neonates with respiratory distress syndrome
71. Decreased alveolarization in baboon survivors with bronchopulmonary dysplasia
72. Neonatal chronic lung disease in extremely immature baboons
73. Chronic lung injury in preterm lambs. Disordered respiratory tract development
74. The effects of preterm delivery and mechanical ventilation on human lung growth
75. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia
76. Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia
77. Pulmonary structural changes in neonatal hyaline membrane disease treated with high pressure artificial respiration
78. Pulmonary complications of oxygen therapy in the neonate. Postmortem study of bronchopulmonary dysplasia with emphasis on fibroproliferative obliterative bronchitis and bronchiolitis
79. Bronchopulmonary dysplasia: The pulmonary pathologic sequel of necrotizing bronchiolitis and pulmonary fibrosis
80. Pathogenesis of bronchopulmonary dysplasia following hyaline membrane disease
81. Ventilator-related pathology in the extremely immature lung
82. Morphometric analysis of the lung in bronchopulmonary dysplasia
83. Different patterns of pulmonary sequelae after hyaline membrane disease: Heterogeneity of bronchopulmonary dysplasia? A clinicopathologic study
84. Pulmonary vascular damage and the development of cor pulmonale following hyaline membrane disease