Autoantibodies: Emerging upstream targets of arrhythmias and sudden death in patients with idiopathic dilated cardiomyopathy

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 10, 2001, Pages 1761-1763

  Ogawa, Satoshi ^a,b   Yoshikawa, Tsutomu ^a  

^a KEIO UNIVERSITY   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

AUTOIMMUNITY; CONGESTIVE CARDIOMYOPATHY; DRUG TARGETING; EDITORIAL; HEART ARRHYTHMIA; HEART VENTRICLE REMODELING; HUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SUDDEN DEATH;

EID: 0034781446     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1440     Document Type: Editorial

References (27)

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3. Frequency and specificity of antiheart antibodies in patients with dilated cardiomyopathy detected using SDS-PAGE and Western blotting
4. Laminine distribution and autoantibodies to laminine in dilated cardiomyopathy and myocarditis
5. Autoantibodies against vimentin in a murine model of myocarditis
6. Antibody-mediated enhancement of calcium permeability in cardiac myocytes
7. Antibodies to ADP-ATP carrier - An autoantigen in myocarditis and dilated cardiomyopathy - Impair cardiac function
8. Cardiac sarcoplasmic reticulum calcium ATPase, an autoimmune antigen in experimental cardiomyopathy
9. Demonstration of organ-specific antibodies against heart mitochondria (anti-M7) in sera from patients with some forms of heart disease
10. Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy
11. Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy
12. Dilated cardiomyopathy defines serum autoantibodies against G-protein-coupled cardiovascular receptors
13. Mapping of a functional autoimmune epitope on the beta1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy
14. Autoimmunity in idiopathic dilated cardiomyopathy: Characterization of antibodies against the beta1-adrenoceptor with positive chronotropic effect
15. Beta1-adrenoceptor autoimmunity in cardiomyopathy
16. Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure
17. Beta-adrenergic effect of antibodies from Chagasic patients and normal human lymphocytes on isolated rat atria
18. A circulating IgG in Chagas' disease which binds to beta-adrenoceptors of myo cardiumand modulates their activity
19. High prevalence of antibodies against beta-1 and beta-2 adrenoceptors in patients with primary electrical cardiac abnormalities
20. Myosin-induced acute myo carditis is a T cell-mediated disease
21. Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy
22. Autoimmunity against the second extracellular loop of β1-adrenergic receptors induces β-adrenergic receptor desensitization and myocardial hypertrophy in vivo
23. Autoantibodies against the β1-adrenoceptor from patients with dilated cardiomyopathy prolong action potential duration and enhance contractility in isolated cardiomyocytes
24. Autoantibodies against the second extracellular loop of beta1-adrenergic receptor predict ventricular tachycardia and sudden death in patients with idiopathic dilated cardiomyopathy
25. Effects of anti-peptide antibodies against the second extracellular loop of human M2 muscarinic acetylcholine receptors on transmembrane potentials and currents in guinea pig ventricular myocytes
26. Differential profile and biochemical effects of antiautonomic membrane receptor antibodies in ventricular arrhythmias and sinus node dysfunction
27. +-ATpase activity in patients with congestive heart failure