Microbial synthesis of three metabolites of a tachykinin receptor antagonist, TAK-637

Journal of Bioscience and Bioengineering

Volumn 92, Issue 3, 2001, Pages 285-287

  Tarui, Naoki ^a   Ikeura, Yoshinori ^a   Natsugari, Hideaki ^a   Nakahama, Kazuo ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Drug metabolite; Large scale; Microbial conversion; Streptomyces; Tachykinin receptor antagonist

Indexed keywords

ALDEHYDES; BACTERIA; CARBOXYLIC ACIDS; FERMENTERS; METABOLITES;

MICROBIAL SYNTHESIS;

MICROBIOLOGY;

DRUG METABOLITE; TACHYKININ RECEPTOR ANTAGONIST; TAK 637; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MELTING POINT; NONHUMAN; SCREENING; STRAIN DIFFERENCE; STREPTOMYCES; THIN LAYER CHROMATOGRAPHY;

ACTINOBACTERIA (CLASS); CAVIA; CAVIA PORCELLUS; STREPTOMYCES; STREPTOMYCES LAVENDULIGRISEUS; STREPTOMYCES SUBRUTILUS; STREPTOMYCES TANASHIENSIS; SUS SCROFA; UNCULTURED ACTINOMYCETE;

EID: 0034781238     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(01)80263-2     Document Type: Article

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