Trypanosoma cruzi: Mucin pseudogenes organized in a tandem array

Experimental Parasitology

Volumn 97, Issue 3, 2001, Pages 173-177

  Allen, Clare L ^a,b   Kelly, John M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; MUCIN; SIALIDASE;

ARTICLE; GENE EXPRESSION; GENE LOCATION; GENETIC ORGANIZATION; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PSEUDOGENE; PULSED FIELD GEL ELECTROPHORESIS; TANDEM REPEAT; TRYPANOSOMA CRUZI;

EID: 0034776101     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.2001.4600     Document Type: Article

References (23)

1. Lytic anti-α-galactosyl antibodies from patients with chronic Chagas’ disease recognise novel O-linked oligosaccharides on mucin-like glycosylphosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi
2. The mechanisms of Trypanosoma cruzi invasion of mammalian cells
3. Molecular karyotype of clone CL Brener chosen for the Trypanosoma cruzi Genome Project
4. Implications of conserved structural motifs in disparate trypanosome surface proteins
5. The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions
6. AU-rich elements in the 3′-untranslated region of a new mucin-type family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency
7. Nucleotide sequence and transcription of a trypomastigote surface antigen gene of Trypanosoma cruzi
8. Passive transfer of a monoclonal antibody specific for a sialic acid-dependent epitope on the surface of Trypanosoma cruzi trypomastigotes reduces infection in mice
9. Two distinct groups of mucin-like genes are differentially expressed in the developmental stages of Trypanosoma cruzi
10. Novel organisation and sequences of five genes encoding all six enzymes for de novo pyrimidine biosynthesis in Trypanosoma cruzi
11. Mechanisms of stage-regulated gene expression in the Kinetoplastida
12. A cyclic AMP inducible gene expressed during the development of infective stages of Trypanosoma cruzi
13. An approach to functional complementation by introduction of large DNA fragments into Trypanosoma cruzi and Leishmania donovani using a cosmid shuttle vector
14. Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi-Homology of the first ORF with the ape family of DNA repair enzymes
15. Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi from killing by human anti-α-galactosyl antibodies
16. Mucin-like glycoprotein genes are closely linked to members of the trans-sialidase superfamily at multiple sites in the Trypanosoma cruzi genome
17. A novel cell surface trans-sialidase of Trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells
18. Mucin-like glycoproteins linked to the membrane by a glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalysed by trans-sialidase in metacyclic forms of Trypanosoma cruzi
19. Sequence homology and absence of mRNA defines a possible pseudogene member of the Trypanosoma cruzi gp85/sialidase multigene family
20. Trypanosoma cruzi adenylyl cyclase is encoded by a complex multigene family
21. Antigenic diversity by the recombination of pseudogenes
22. Role of sialic acid in resistance of Trypanosoma cruzi trypomastigotes to complement
23. FL-160 proteins of Trypanosoma cruzi are expressed from a multigene family and contain two distinct epitopes that mimic mammalian nervous tissue