In vivo efficacy of telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 11, 2001, Pages 3250-3252

  Okamoto, H ^a   Miyazaki, S ^a   Tateda, K ^a   Ishii, Y ^a   Yamaguchi, K ^a  

^a Aventis Pharma Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CEFDINIR; CLARITHROMYCIN; ERYTHROMYCIN; LEVOFLOXACIN; PENICILLIN G; TELITHROMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; HAEMOPHILUS INFLUENZAE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE; ERYTHROMYCIN; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HALF-LIFE; KETOLIDES; MACROLIDES; MALE; MICE; MICE, INBRED CBA; MICE, INBRED ICR; MICROBIAL SENSITIVITY TESTS; PNEUMOCOCCAL INFECTIONS; RESPIRATORY TRACT INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 0034775109     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.11.3250-3252.2001     Document Type: Article

References (13)

1. In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae
2. Comparative antimicrobial activity and kill-curve investigations of novel ketolide antimicrobial agents (HMR3004 and HMR3647) tested against Haemophilus influenzae and Moraxella catarrhalis strains
3. Antibacterial activity of telithromycin (HMR3647) in relation to in vitro simulated human plasma kinetics
4. In vivo efficacy of the new ketolide telithromycin (HMR3647) in murine infection models
5. New tables for multiple comparisons with a control
6. 50 and its error by means of logarithmic probit graph paper
7. New murine model of bronchopneumonia due to cell-bound Haemophilus influenzae
8. Assays for TE-031(A-56268) in body fluids. I. Microbiological assay
9. Comparative in vitro activity of telithromycin (HMR3647), three macrolides, amoxicillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan
10. Method of measuring azithromycin concentration in body fluid by bioassay and high-performance liquid chromatography
11. Noncompromised penicillin-resistant pneumococcal pneumonia CBA/J mouse model and comparative efficacies of antibiotics in this model
12. In vitro and in vivo antibacterial activities of CS-834, a new oral carbapenem
13. In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens