The differential distribution of acetylated and detyrosinated alpha-tubulin in the microtubular cytoskeleton and primary cilia of hyaline cartilage chondrocytes

Journal of Anatomy

Volumn 199, Issue 4, 2001, Pages 393-405

  Anthony Poole, C ^a   Zhang, Zi Jun ^a   Ross, Jacqueline M ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Chick embryo sterna; Confocal microscopy; Electron microscopy; Immunohistochemistry; Microtubules

Indexed keywords

ALPHA TUBULIN; ANTIBODY; COLLAGEN; PROTEIN;

ACETYLATION; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CARTILAGE CELL; CELL NUCLEUS; CELL ORGANELLE; CELL SURFACE; CELL ULTRASTRUCTURE; CELL VACUOLE; CENTRIOLE; CENTROSOME; CHICK EMBRYO; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; EMBRYO; EXOCYTOSIS; EXTRACELLULAR MATRIX; FROZEN SECTION; GOLGI COMPLEX; HYPOTHESIS; MICROTUBULE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PSEUDOPODIUM; SIGNAL TRANSDUCTION; STAINING; STERNUM; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALIA; STERNA;

EID: 0034773122     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-7580.2001.19940393.x     Document Type: Article

References (70)

1. Experimental model for studying the primary cilia in tissue culture cells
2. Role of motor proteins in organizing the endoplasmic reticulum and Golgi apparatus
3. Mechanoreception at the cellular level: The detection, interpretation and diversity of responses to mechanical signals
4. Cilia in sense organs
5. Transmembrane signalling in cilia and flagella
6. Microtubule organising centers
7. Alteration in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression
8. Post-translational modifications of α-tubulin: Detyrosination and acetylation differentiate populations of interphase microtubules in cultured cells
9. Regulated exocytosis
10. Heterogeneous distribution of the cAMP receptor protein RH in the nervous system: Evidence for its intracellular accumulation on microtubules, microtubule-organising centers, and in the area of the Golgi complex
11. Microtubule-membrane interactions in cilia and flagella
12. Organisation of the chondrocyte cytoskeleton and its response to changing mechanical conditions in organ culture
13. Microtubules are potential regulators of growth-plate chondrocyte differentiation and hypertrophy
14. Ultrastructural colocalization of tyrosinated and detyrosinated α-tubulin in interphase and mitotic cells
15. The ciliary necklace: A ciliary membrane specialisation
16. Selective targeting of somatostatin receptor 3 to neuronal cilia
17. Confocal microscopy of whole mount embryonic cartilage: Intracellular localisation of F-actin, chick prolyl hydroxylase and type II collagen mRNA
18. Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose
19. Cellular tensegrity: Defining new rules of biological design that govern the cytoskeleton
20. 1 cells: Effects of colcemid and taxol on cilia formation and resorption
21. The role of microtubules in the regulation of proteoglycan synthesis in chondrocytes under hydrostatic pressure
22. Functional morphology of insect mechanoreceptors
23. The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression
24. Functional components of microtubule-organizing centers
25. Ultrastructural study of chondrocytes from fibrillated and non-fibrillated human osteoarthritic cartilage
26. Role of microtubules in the organisation of the Golgi apparatus
27. A molecular marker for centriole maturation in the mammalian cell cycle
28. Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose
29. Three dimensional organization of stable microtubules and the Golgi apparatus in the somata of developing chick sensory neurons
30. Chondrocyte integrin expression and function
31. The multiple forms of tubulin: Different gene products and covalent modifications
32. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
33. Single cilia in the articular cartilage of the cat
34. Pre-natal development of rat nasal epithelia. V. Freeze-fracturing on necklaces of primary and secondary cilia of olfactory and respiratory cilia
35. The structure and function of sensory cilia
36. Synchronised shift in localisation of the Golgi complex and the microtubule organizing center in the terminal phase of cytokinesis
37. Cold and metabolic inhibitor effects on cytoplasmic microtubules and the Golgi complex in cultured rat epiphyseal chondrocytes
38. Functions of the Golgi complex in cell division: Formation of cell-matrix contacts and cell-cell communication channels in the terminal phase of cytokinesis
39. The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules
40. Microtubule dynamics in vitro are regulated by the tubulin isotype composition
41. Monoclonal antibodies specific for an acetylated form of α-tubulin recognize the antigen in cilia and flagella from a variety of organisms
42. Microtubules containing acetylated α-tubulin in mammalian cells in culture
43. Hyaline cartilage in long bone development
44. Analysis of the morphology and function of primary cilia in connective tissues: A cellular cybernetic probe?
45. Confocal analysis of primary cilia structure and colocalisation with the Golgi apparatus in chondrocytes and aortic smooth muscle cells
46. Is signal transduction modulated by an interaction between heterotrimeric G-protein and tubulin?
47. Unravelling the tangled web at the microtubule-organising center
48. Monoclonal antibody ID5: Epitope characterisation and minimal requirements for the recognition of polyglutamylated alpha and beta tubulin
49. Dynamic and stable populations of microtubules in cells
50. Post-translational modification and microtubule stability
51. Analysis and modelling of the primary cilium bending response to fluid shear
52. Intracellular membranes in the synthesis, transport and metabolism of proteoglycans
53. Spatial and temporal colocalization of the Golgi apparatus and microtubules rich in detyrosinated tubulin
54. Golgi-cilium complex in rabbit ciliary process cells
55. Microtubules and the organisation of the Golgi complex
56. Reorganisation of the Golgi complex in association with mitosis: Redistribution of mannosidase II to the endoplasmic reticulum and effects of brefeldin A
57. Relationship between the Golgi complex and microtubules enriched in detyrosinated or acetylated α-tubulin: Studies on cells recovering from nocodazole and cells in the terminal phase of cytokinesis
58. Role of microtubules and the organisation of the Golgi complex
59. The effects of tensile load on the metabolism of cultured chondrocytes
60. Intracellular features of type II procollagen and chondroitin sulfate proteoglycan synthesis in chondrocytes
61. Turnover of the carboxy-terminal tyrosine of alpha tubulin and means of reaching elevated levels of detyrosination in living cells
62. Centrioles, cilia and flagella
63. Primary cilia in normal and pathological tissues
64. Primary cilia in cultured mammalian cells. Detection with an antibody against detyrosinated alpha-tubulin (ID5) and by electron microscopy
65. Cilia of adult canine articular cartilage
66. Cilia of neonatal articular chondrocytes: Incidence and morphology
67. Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies
68. Golgi membranes are absorbed into and re-emerge from the ER during mitosis