Antispasmodic/analgesic associations in primary dysmenorrhea double-blind crossover placebo-controlled clinical trial

International Journal of Clinical Pharmacology Research

Volumn 21, Issue 1, 2001, Pages 21-29

  De los Santos, A R ^a   Zmijanovich, R ^a   Perez Macri S ^a   Marti M L ^a   Di Girolamo, G ^a  

^a NONE   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CLONIXIN LYSINE; PARACETAMOL; PARGEVERINE; PLACEBO; SCOPOLAMINE BUTYL BROMIDE; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DYSMENORRHEA; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MENSTRUATION; PAIN ASSESSMENT; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SYMPTOM;

ACETAMINOPHEN; ADULT; ANALGESICS, NON-NARCOTIC; BUTYLSCOPOLAMMONIUM BROMIDE; CLONIXIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; DYSMENORRHEA; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYSINE; MANDELIC ACIDS; PAIN; PARASYMPATHOLYTICS; PARITY;

EID: 0034770261     PISSN: 02511649     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Primary dysmenorrhea
2. Menstrual prostaglandins and dysmenorrhea. Modulation by nonsteroidal anti-inflammatory agents
3. Nitric oxide in the endometrium
4. Efficacy of minor analgesics in primary dysmenorrhea: A systematic review
5. Rofecoxib, a specific cyclooxygenase-2 inhibitor in primary dysmenorrhea: A randomised controlled trial
6. Lysine clonixinate in the treatment of primary dysmenorrhea
7. Antispasmodic action of propinox on the isolated human gallbladder: Possible mechanism of action
8. Comparison of the isolated human and guinea-pig gallbladder strip models in the assessment of antispasmodic drugs
9. Propinox plus lysine clonixinate administered orally in abdominal colic pain. Prospective randomized double-blind clinical study controlled with placebo plus hyoscine N-butylbromide
10. Double-blind clinical study with i.m. or i.v. administration of propinox in association with lysine clonixinate or dipyrone in the treatment of upper abdominal pain
11. Propinox in biliary colic: A multicenter randomized prospective parallel double-blind study of three doses of propinox versus placebo in acute biliary colic pain
12. Assessment of efficacy and tolerance of propinox in association with lysine clonixinate in the treatment of abdominal colic pain
13. Prepinox/lysine clonixinate association in the treatment of acute pain
14. Analgesic-antispasmodic effect and safety of lysine clonixinate and L-hyoscinbutylbromide in the treatment of dysmenorrhea
15. Nonsteroidal anti-inflammatory drugs for heavy menstrual bleeding
16. Use and benefits of nonsteroidal anti-inflammatory drugs
17. Overall approach to the management of dysmenorrhea
18. Newer concepts in dysmenorrhea research
19. Effects of lysine clonixinate and indomethacin on lipoxygenase and cyclooxygenase activities in isolated colon segments from patients with neoplasia
20. Effects of nonsteroidal antiinflammatory agents on cyclooxygenase and lipoxygenase activities in human gallbladder
21. Clinical trials: Specific problems associated with the use of a placebo control group