Sequential multilocus fluorescence in situ hybridization can detect complex patterns of increased gene dosage at the single cell level in tissue sections

Laboratory Investigation

Volumn 81, Issue 10, 2001, Pages 1457-1459

  Walch, Axel ^a,b   Bink, Karin ^a,b   Hutzler, Peter ^b   Böwering, Katharina ^a   Letsiou, Ioanna ^a   Zitzelsberger, Horst ^b   Braselmann, Herbert ^b   Stein, Hubert ^a   Höfler, Heinz ^a,b   Werner, Martin ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL LEVEL; COMPARATIVE STUDY; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; HISTOLOGY; HUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034769659     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780359     Document Type: Article

References (4)

1. Evolution of neoplastic cell lineages in Barrett oesophagus
2. 17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus
3. Fluorescence in situ hybridization for detecting erbB-2 amplification in breast tumor tine needle aspiration biopsies
4. 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast