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Volumn 34, Issue 2, 2001, Pages 71-80
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Process characterization for metal-affinity chromatography of an Fc fusion protein: A design-of-experiments approach
a a a a |
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Author keywords
Factorial design; IMAC; Immobilized metal affinity chromatography; Process robustness; Process validation
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Indexed keywords
CHROMATOGRAPHY;
COMPOSITION;
FUSION REACTIONS;
PURIFICATION;
ROBUSTNESS (CONTROL SYSTEMS);
METAL-AFFINITY;
PROTEINS;
HYBRID PROTEIN;
IMMUNOGLOBULIN FC FRAGMENT;
METAL;
AFFINITY CHROMATOGRAPHY;
ANIMAL CELL;
ARTICLE;
EXPERIMENT;
METHODOLOGY;
NONHUMAN;
PROTEIN ANALYSIS;
PROTEIN PURIFICATION;
TECHNIQUE;
VALIDATION PROCESS;
ANIMALS;
CHO CELLS;
CHROMATOGRAPHY, AFFINITY;
CHROMATOGRAPHY, GEL;
CLINICAL TRIALS, PHASE I;
CRICETINAE;
ENZYMES, IMMOBILIZED;
FACTOR ANALYSIS, STATISTICAL;
IMMUNOGLOBULIN FC FRAGMENTS;
IMMUNOGLOBULIN G;
METALS;
RECOMBINANT FUSION PROTEINS;
REPRODUCIBILITY OF RESULTS;
RESEARCH DESIGN;
STAPHYLOCOCCAL PROTEIN A;
ANIMALIA;
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EID: 0034769438
PISSN: 08854513
EISSN: None
Source Type: Journal
DOI: 10.1042/BA20010019 Document Type: Article |
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Times cited : (20)
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References (21)
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