Mammalian DNA methyltransferases show different subnuclear distributions

Journal of Cellular Biochemistry

Volumn 83, Issue 3, 2001, Pages 373-379

  Margot, Jean B ^a   Cristina Cardoso, M ^a   Leonhardt, Heinrich ^a,b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b Franz Volhard Klinik   (Germany)

Author keywords

DNA methylation; DNA methyltransferase; DNA replication; Dnmt1; Dnmt3; PCNA; Replication foci

Indexed keywords

DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA METHYLATION; DNA REPLICATION; ENZYME ASSAY; IMMUNOFLUORESCENCE; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CELLS, CULTURED; COS CELLS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA REPLICATION; EPITOPES; HUMANS; METHYLTRANSFERASES; MICE; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; PROTEIN STRUCTURE, TERTIARY; S PHASE; TRANSFECTION;

MAMMALIA;

EID: 0034766776     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.1236     Document Type: Article

References (21)

1. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
2. Immunofluorescence techniques in cell cycle studies
3. DNA methyltransferase is actively retained in the cytoplasm during early development
4. Properties and localization of DNA methyltransferase in preimplantation mouse embryos: Implications for genomic imprinting
5. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
6. Eukaryotic DNA methylation as an evolutionary device
7. In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b
8. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
9. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
10. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
11. DNA methylation, genomic imprinting, and mammalian development
12. Role for DNA methylation in genomic imprinting
13. Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci
14. Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure
15. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
16. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
17. DNA hypomethylation can activate Xist expression and silence X-linked genes
18. CpG methylation is maintained in human cancer cells lacking DNMT1
19. Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene
20. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
21. New 5′ regions of the murine and human genes for DNA (cytosine-5)- methyltransferase