The ubiquitin-proteasome system and neurodegenerative disease

Brain and Nerve

Volumn 53, Issue 10, 2001, Pages 935-942

  Tanaka, K ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Neurodegeneration; Parkinson's disease; Proteasome; Ubiquitin

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN; PROTEASOME; REACTIVE OXYGEN METABOLITE; UBIQUITIN;

DEGENERATIVE DISEASE; HUMAN; NERVE DEGENERATION; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN FOLDING; REVIEW;

CYSTEINE ENDOPEPTIDASES; HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; MULTIENZYME COMPLEXES; NEURODEGENERATIVE DISEASES; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN;

EID: 0034766344     PISSN: 00068969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (20)

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9. Protein, nucleotide identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
10. The U box modified RING finger - A common domain in ubiquitination
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15. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substate of parkin
16. Parkin is linked to the ubiquitin pathway
17. Ubiquitination of a new form of a-synuclein by parkin from human brain: Implications for Parkinson's disease
18. Impairment of the ubiquitin-proteasome system by protein aggregation
19. Aggresomes, inclusion bodies and protein aggregation