Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta

Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 10, 2001, Pages 1372-1374

  Aoki, S ^a   Ye, Y ^a   Higuchi, K ^a   Takashima, A ^a   Tanaka, Y ^a   Kitagawa, I ^a   Kobayashi, M ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Indole alkaloid; Marine sponge; Nitric oxide synthase

Indexed keywords

APLYSINOPSIN; INDOLE ALKALOID; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; SPONGE (PORIFERA); STRUCTURE ANALYSIS;

ANIMALS; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; OMEGA-N-METHYLARGININE; OXIDATION-REDUCTION; PORIFERA; RATS; RATS, WISTAR; SPECTROPHOTOMETRY, INFRARED; TRYPTOPHAN;

EID: 0034765865     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.49.1372     Document Type: Article

References (15)