Direct comparison of detection systems used for the development of single-cell genetic tests in preimplantation genetic diagnosis

Journal of Assisted Reproduction and Genetics

Volumn 18, Issue 10, 2001, Pages 557-565

  Blake, Deborah L ^a   Dean, Nicola L ^a   Knight, Casey ^a   Tan, Seang Lin ^a   Ao, Asangla ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Allele dropout; Fluorescence multiplex PCR; Preimplantation genetic diagnosis; Short tandem repeats

Indexed keywords

HETERODUPLEX;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYSTIC FIBROSIS; DIAGNOSTIC ACCURACY; EMBRYO; FLUORESCENCE ANALYSIS; GENE AMPLIFICATION; GENE LOCUS; GENETIC SCREENING; HUMAN; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENETIC SCREENING; HUMANS; MALE; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PREGNANCY; PREIMPLANTATION DIAGNOSIS; PRENATAL DIAGNOSIS; SINGLE-BLIND METHOD;

EID: 0034765763     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011958008240     Document Type: Article

References (22)

1. Preimplantation diagnosis of single gene disorders by two-step oocyte genetic analysis using first and second polar body
2. An analysis of the demand for and cost of preimplantation genetic diagnosis in the United Kingdom
3. Birth of healthy children after preimplantation diagnosis of thalassemias
4. Preimplantation diagnosis for Huntington's disease (HD): Clinical application and analysis of the HD expansion in affected embryos
5. Fluorescent PCR and automated fragment analysis for the clinical application of preimplantation genetic diagnosis of myotonic dystrophy (Steinhert's disease)
6. A technique for eliminating allele specific amplification failure during DNA amplification of heterozygous cells for preimplantation diagnosis
7. Preimplantation genetic diagnosis of inherited cancer: Familial adenomatous polyposis coli
8. Allelic drop-out and preferential amplification in single cells and human blastomeres: Implications for preimplantation diagnosis of sex and cystic fibrosis
9. High-sensitive fluorescent DNA sequencing and its application for detection and massscreening of point mutations
10. Assessment of multiplex fluorescent PCR for screening single cells for trisomy 21 and single gene defects
11. Single-sperm typing: Determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers
12. Development and validation of laboratory procedures for preimplantation diagnosis of Duchenne muscular dystrophy
13. Birth of a normal girl after in vitro fertilization and preimplantation diagnostic testing for cystic fibrosis
14. Co-amplification of the cystic fibrosis delta F508 mutation with the HLA DQA1 sequence in single cell PCR: Implications for improved assessment of polar bodies and blastomeres in preimplantation diagnosis
15. Allele dropout in polar bodies and blastomeres
16. Multiplex PCR of polymorphic markers flanking the CFTR gene: A general approach for preimplantation genetic diagnosis of cystic fibrosis
17. Controlling misdiagnosis errors in preimplantation genetic diagnosis: A comprehensive model encompassing extrinsic and intrinsic sources of error
18. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
19. Successful outcome with day 4 embryo transfer after preimplantation genetic diagnosis for genetically transmitted diseases
20. Preimplantation genetic diagnosis of DiGeorge syndrome
21. Advantages of day 4 embryo transfer in patients undergoing preimplantation genetic diagnosis of aneuploidy
22. Preimplantation genetics