Deletion of the cnxE gene encoding the gephyrin-like protein involved in the final stages of molybdenum cofactor biosynthesis in Asperillus nidulans

Molecular Genetics and Genomics

Volumn 266, Issue 3, 2001, Pages 445-453

  Millar, L ^a   Heck, I ^b   Sloan, J ^c   Kana'n, G ^a,d   Kinghorn, J ^a   Unkles, S ^c  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c MONASH UNIVERSITY   (Australia)

^d MUTAH UNIVERSITY   (Jordan)

Author keywords

cnxE; Fungi; Molybdenum cofactor

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; FUNGAL PROTEIN; HISTIDINE; MOLYBDOPTERIN; NITRATE REDUCTASE; PROTEIN CNXE; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ARTICLE; ASPERGILLUS NIDULANS; BACTERIUM MUTANT; BIOSYNTHESIS; DELETION MUTANT; ENZYME INDUCTION; ESCHERICHIA COLI; GENE DELETION; GENE ISOLATION; GENE STRUCTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; BASE SEQUENCE; BINDING SITES; BLOTTING, SOUTHERN; CARRIER PROTEINS; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; COENZYMES; DNA, COMPLEMENTARY; DNA, FUNGAL; ENZYME PRECURSORS; GENE DELETION; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; METALLOPROTEINS; MOLECULAR SEQUENCE DATA; MOLYBDENUM; MULTIENZYME COMPLEXES; MUTATION; NITRATE REDUCTASE; NITRATE REDUCTASES; PLASMIDS; PTERIDINES;

ASPERGILLUS; BACTERIA (MICROORGANISMS); EMERICELLA NIDULANS; ESCHERICHIA COLI; FUNGI; HYPSOPHRYS NICARAGUENSIS; PROKARYOTA;

EID: 0034765272     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380100543     Document Type: Article

References (47)

1. Basic local alignment search tool
2. ModE-dependent molybdate regulation of the molybdenum cofactor operon moa in Escherichia coli
3. The Aspergillus nidulans cnxF gene and its involvement in molybdopterin biosynthesis
4. Molybdate metabolism in Aspergillus nidulans. I. Mutations affecting nitrate reductase and xanthine dehydrogenase
5. Regulation of the chlA locus of Escherichia coli K12: Involvement of molybdenum cofactor
6. Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans
7. Cloning and characterisation of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans
8. Aspergillus nidulans
9. The induction and repression of nitrate reductase in the fungus Aspergillus nidulans
10. Kinetic studies of the induction of nitrate reductase and cytochrome c reductase in the fungus Aspergillus nidulans
11. Chlorate toxicity in Aspergillus nidulans: The selection and characterisation of chlorate resistant mutants
12. Independently segregating loci concerned with nitrate reductase activity in Aspergillus nidulans
13. Genetic control of nitrate reduction in Aspergillus nidulans
14. High efficiency transformation of E. coli by high voltage electroporation
15. Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes α-actin
16. Phenotypic restoration by molybdate of nitrate reductase activity in chlD mutants of Escherichia coli
17. Molybdenum cofactor biosynthesis in Neurospora crassa: Biochemical characterisation of pleiotropic molybdoenzyme mutants nit-7, nit-8, nit-9A, B and C
18. Biogenesis of molybdenum cofactors
19. In vitro system for molybdopterin biosynthesis
20. Involvement of chlA, E, M and N loci in Escherichia coli molybdopterin biosynthesis
21. Isolation and characterisation of the crnA-niiA-niaD gene cluster for nitrate assimilation in Aspergillus nidulans
22. Molybdenum cofactor biosynthesis in Escherichia coli mod and mog mutants
23. The Drosophila molybdenum cofactor gene cinnamon is homologous to three Escherichia coli cofactor proteins and to the rat protein Gephyrin
24. In vitro restoration of nitrate reductase: Investigation of Aspergillus nidulans and Neurospora crassa nitrate reductase mutants
25. Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization
26. The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis
27. Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli
28. In vitro incorporation of nascent molybdenum cofactor into human sulfite oxidase
29. The Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesis
30. Molybdoenzymes and molybdenum cofactor in plants
31. Cloning and complete nucleotide sequence of the Escherichia coli chlEN operon involved in molybdopterin biosynthesis
32. A common cofactor for nitrate reductase and xanthine dehydrogenase which also regulates the synthesis of nitrate reductase
33. Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein
34. Cloning of seven differently complementing DNA fragments with chl functions from Escherichia coli K12
35. Molecular genetic analysis of the moa operon of Escherichia coli K12 required for molybdenum cofactor biosynthesis
36. Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation
37. The purine degradation pathway, genetics, biochemistry and regulation
38. Molybdenum cofactor biosynthesis. The plant protein Cnx1 binds molybdopterin with high affinity
39. Molybdenum cofactor biosynthesis: The Arabidopsis thaliana cDNA cnx1 encodes a multifunctional two-domain protein homologous to a mammalian neuroprotein, the insect protein Cinnamon and three Escherichia coli proteins
40. The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells
41. Gene organisation in industrial filamentous fungi
42. The Aspergillus nidulans cnxABC locus is a single gene encoding two catalytic domains required for synthesis of precursor Z, an intermediate in molybdenum cofactor biosynthesis
43. Eukaryotic molybdopterin synthase. Biochemical and molecular studies of Aspergillus nidulans cnxG and cnxH mutants
44. Transduction of nitrate reductase loci of Escherichia coli by phages P1 and λ
45. Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC