Alpha adrenergic activation and hemoglobin mediated contraction in the isolated rat thoracic aorta

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

Volumn 29, Issue 5, 2001, Pages 367-380

  Kim, H W ^a   Tai, J ^a   Greenburg, A G ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CHELATION; NITROGEN OXIDES; POTASSIUM COMPOUNDS;

ALPHA ALDRENERGIC ACTIVATION;

BIOTECHNOLOGY;

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHELATING AGENT; EGTAZIC ACID; HEMOGLOBIN; NITRIC OXIDE; NORADRENALIN; PHENTOLAMINE; POTASSIUM CHLORIDE; VERAPAMIL; ADRENERGIC ALPHA AGONISTS; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BLOOD SUBSTITUTE; CALCIUM;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; RAT; THORACIC AORTA; VASODILATATION; ANIMAL; DRUG EFFECT; METABOLISM; PHYSIOLOGY; RAT STRAIN; SOLUTION AND SOLUBILITY; VASOCONSTRICTION;

ANIMALIA;

ADRENERGIC ALPHA-AGONISTS; ANIMAL; AORTA, THORACIC; BLOOD SUBSTITUTES; CALCIUM; CALCIUM CHANNEL BLOCKERS; EGTAZIC ACID; HEMOGLOBINS; MALE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SOLUTIONS; VASOCONSTRICTION; VERAPAMIL;

EID: 0034763199     PISSN: 10731199     EISSN: None     Source Type: Journal    
DOI: 10.1081/BIO-100106920     Document Type: Article

References (24)

1. A clinical safety trial of stroma-free hemoglobin
2. The effect of stroma-free hemoglobin solution on the isolated perfused rabbit ventricular septum
3. Coronary constrictor effect of stroma-free hemoglobin solutions
4. Systemic and pulmonary hypertension after resuscitation with cell-free hemoglobin
5. Hemoglobin inhibits endotheliumdependent relaxation to acetylcholine in human coronary arteries in vivo
6. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta
7. The mechanisms by which hemoglobin inhibits the relaxation of rabbit aorta induced by nitrovasodilators, nitric oxide, or bovine retractor penis inhibitory factor
8. The kinetics and equilibria of the reactions of nitric oxide with sheep hemoglobin
9. Pharmacodynamic characterization of hemoglobin induced vasoactivity in isolated rat thoracic aorta
10. Depression of contractile responses in rat aorta by spontaneously released endotheliumderived relaxing factor
11. Recombinant human hemoglobin (rHb 1.1) selectively inhibits vasorelaxation elicited by nitric oxide donors in rabbit isolated aortic rings
12. Molecular biology of calcium channels in the cardiovascular system
13. Norepinephrine release during vasoconstriction induced by cross-linked hemoglobin
14. Role of adrenergic mechanisms in the pressor effect of diaspirin cross-linked hemoglobin
15. Cyclic nucleotide dependent relaxation invascular smooth muscle
16. Regulation of vascular smooth muscle tone
17. Effects of metabolic inhibition on cytoplasmic calcium and contraction in smooth muscle of rat portal vein
18. Hemoglobininduced contraction of pig pulmonary veins
19. Noradrenaline, beta-adrenoreceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat
20. Clinical trial of a hemoglobin based blood substitute in patients with sickle cell anemia
21. Initial clinical experience with recombinant human hemoglobin
22. Resuscitation with diaspirin crosslinked hemoglobin in a pig model of hemorrhagic shock
23. Resuscitation of the injured patients with polymerized stroma-free hemoglobin does not produce systemic or pulmonary hypertension
24. Middel cereral artery blood velocity and plasma catecholamines during exercise