Measles virus interactions with cellular receptors: Consequences for viral pathogenesis

Journal of NeuroVirology

Volumn 7, Issue 5, 2001, Pages 391-399

  Schneider Schaulies, J ^a   Ter Meulen, V ^a   Schneider Schaulies, S ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Akt kinase; CD150; CD46; Immunosuppression; Measles virus

Indexed keywords

CD150 ANTIGEN; CELL RECEPTOR; MEMBRANE COFACTOR PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS RECEPTOR;

CELL PROLIFERATION; CELL SURFACE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; FATALITY; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOID CELL; MEASLES VIRUS; MORBIDITY; MORTALITY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RASH; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; VIRUS PATHOGENESIS;

ANTIGENS, CD; ANTIGENS, CD46; ANTIGENS, SURFACE; BRAIN; CYTOKINES; ENCEPHALITIS, VIRAL; G0 PHASE; GLYCOPROTEINS; HEMAGGLUTININS, VIRAL; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOGLOBULINS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; LYMPHOPENIA; MEASLES VIRUS; MEMBRANE FUSION; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; NEUROGLIA; NEURONS; OPPORTUNISTIC INFECTIONS; PNEUMONIA, VIRAL; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION; SUBACUTE SCLEROSING PANENCEPHALITIS; T-LYMPHOCYTE SUBSETS; VIRAL FUSION PROTEINS; VIRAL MATRIX PROTEINS; VIREMIA; VIRULENCE; VIRUS REPLICATION;

MEASLES VIRUS;

EID: 0034762791     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/135502801753170246     Document Type: Review

References (88)

1. The significance of measles virus antigen and genome distribution in the CNS in SSPE for mechanisms of viral spread and demyelination
2. Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation
3. Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis
4. Disruption of Akt kinase activation is important for immunosuppression induced by measles virus
5. Structural basis for paramyxovirus mediated membrane fusion
6. Differential receptor usage by measles virus strains
7. The role of subtilisin-like pro-protein convertases for cleavage of the measles virus fusion glycoprotein in different cell types
8. Measles virus-mononuclear cell interactions
9. Mapping of the primary binding site of measles virus to its receptor CD46
10. Interferon-resistant subpopulations in several strains of measles virus: Positive selection by growth of the virus in brain tissue
11. Crystal structure of two CD46 domains reveals an extended measles virus-binding surface
12. A matrix-less measles virus is infectious and elicits extensive cell fusion: Consequences for propagation in the brain
13. Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence
14. The epidemiology of measles: Thirty years of vaccination
15. A novel receptor involved in T-cell activation
16. The human CD46 molecule is a receptor for measles virus (Edmonston strain)
17. Detection and identification of virus specific oligoclonal IgG in unconcentrated cerebrospinal fluid by immuno blot technique
18. The H gene of rodent brain-adapted measles virus confers neurovirulence to the Edmonston vaccine strain
19. Observation of measles virus cell-to-cell spread in astrocytoma cells by using a green fluorescent protein-expressing recombinant virus
20. Measles virus-induced immunosuppression in vitro is associated with deregulation of G1 cell cycle control proteins
21. CD150 (SLAM) is a receptor for measles virus, but is not involved in viral contact-mediated proliferation inhibition
22. Measles virus spread by cell-cell contacts: Uncoupling of contact-mediated receptor (CD46) downregulation from virus uptake
23. Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cells
24. Modulation of immune system function by measles virus infection: Role of soluble factor and direct infection
25. Measles virus receptor properties are shared by several CD46 isoforms differing in extracellular regions and cytoplasmic tails
26. Electroencephalographic abnormality in "uncomplicated" childhood diseases
27. Measles virus
28. Differential CD4 T cell activation in measles
29. Measles virus infects human dendritic cells and blocks their allostimulatory properties for CD4+ T cells
30. Measles virus-substance P receptor interaction: Jurkat lymphocytes transfected with substance P receptor cDNA enhance measles virus fusion and replication
31. Human CD46 enhances nitric oxide production in mouse macrophages in response to measles virus infection in the presence of gamma interferon: Dependence on the CD46 cytoplasmic domains
32. Transgenic mice expressing human measles virus (MV) receptor CD46 provide cells exhibiting different permissivities to MV infections
33. CDw150(SLAM) is a receptor for a lymphotropic strain of measles virus and may account for the immunosuppressive properties of this virus
34. A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells
35. Mechanism of suppression of cell-mediated immunity by measles virus
36. Human receptor for measles virus (CD46) enhances nitric oxide production and restricts virus replication in mouse macrophages by modulating the production of alpha/beta-interferon
37. Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation
38. Functional modulation of human macrophages through CD46 (measles virus receptor): Production of IL-12 p40 and nitric oxide in association with recruitment of protein-tyrosine phosphatase SHP-1 to CD46
39. Paramyxovirus fusion: A hypothesis for changes
40. Peptides from conserved regions of paramyxovirus fusion proteins are potent inhibitors of viral fusion
41. Sequence and structure alignment of paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin
42. Measles virus spread between neurons requires cell contact but not CD46 expession, syncytium formation, or extracellular virus production
43. Measles infections in rodents
44. Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats
45. Clinical isolates of measles virus use CD46 as a cellular receptor
46. Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus
47. Measles virus infection and replication in undifferentiated and differentiated human neuronal cells in culture
48. Downregulation of endothelin receptor mRNA synthesis in C6 rat astrocytoma cells by persistent measles virus and canine distemper virus infections
49. Recombinant measles viruses expressing altered hemagglutinin (H) genes: Functional separation of mutations determining H antibody escape from neurovirulence
50. Measles virus spread and pathogenesis in genetically modified mice
51. Evidence that measles virus hemagglutinin initiates modulation of leukocyte function-associated antigen 1 expression
52. Detection of measles virus genome directly from clinical samples by reverse transcriptase-polymerase chain reaction and genetic variability
53. Measles virus infection causes transient depletion of activated T cells from peripheral circulation
54. Cell cycle arrest during measles virus infection: A G0-like block leads to suppression of Retinoblastoma protein expression
55. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus
56. Measles virus haemagglutinin induces down-regulation of gp57/67, a molecule involved in virus binding
57. Measles virus-induced immune suppression in the cotton rat (Sigmodon hispidus) model depends on viral glycoproteins
58. Measles virus-induced immunosuppression in cotton rats is associated with cell cycle retardation in uninfected lymphocytes
59. Absence of measles virus receptor (CD46) in lesions of subacute sclerosing panencephalitis brains
60. The hemagglutinin protein is an important determinant for measles virus tropism for dendritic cells in vitro and immunosuppression in vivo
61. On changes in the cerebrospinal fluid during measles
62. Measles virus on throat swabs from measles patients use signalling lymphocytic activation molecule (CDw150) but not CD46 as a cellular receptor
63. Immunodeficiency virus cDNA synthesis in resting T lymphocytes is regulated by T cell activation signals and dendritic cells
64. Soluble and membrane-bound forms of signalling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes
65. A transgenic mouse model for measles virus infection of the brain
66. Central nervous system affection in connection with "ordinary" measles
67. Measles virus strain variations
68. Sequence divergence of measles virus haemagglutinin during natural evolution and adaptation to cell culture
69. Measles-induced suppression of lymphocyte proliferation
70. Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro
71. Physical association of moesin and CD46 as a receptor complex for measles virus
72. Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains
73. Receptor (CD46) modulation and complement-mediated lysis of uninfected cells after contact with measles virus-infected cells
74. Measles virus induced immunosuppression: Targets and effector mechanisms
75. Measles Virus
76. Cell type-specific MxA-mediated inhibition of measles virus transcription in human brain cells
77. Measles virus-induced down-regulation of CD46 is associated with enhanced sensitivity to complement-mediated lysis of infected cells
78. Cell cycle arrest rather than apoptosis is associated with measles virus contact-mediated immunosuppression in vitro
79. Suppression of antigen-specific T cell proliferation by measles virus infection: Role of a soluble factor in suppression
80. The hemagglutinin of recent measles virus isolates induces cell fusion in a marmoset cell line, but not in other CD46-positive human and monkey cell lines, when expressed together with the F protein
81. SLAM (CDw150) is a cellular receptor for measles virus
82. Spread of measles virus through axonal pathways into limbic structures in the brain of Tab -/- mice
83. Measles virus-induced immunosuppression in vitro is independent of complex glycosylation of viral glycoproteins and hemifusion
84. Proteolytic cleavage of the fusion protein but not membrane fusion is required for measles virus-induced immunosuppression in vitro
85. Inhibition of measles virus infection and fusion with peptides corresponding to the leucine zipper region of the fusion protein
86. Measles virus: Both the hemagglutinin and fusion glycoproteins are required for fusion
87. Mode of entry of morbilliviruses
88. Measles virus inhibits mitogen-induced T cell proliferation but does not directly perturb the T cell activation process inside the cell