Effects of high-energy electrons and gamma rays directly on protein molecules

Journal of Pharmaceutical Sciences

Volumn 90, Issue 10, 2001, Pages 1637-1646

  Kempner, E S ^a,b  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Direct effects; Macromolecules; Radiation; Target theory

Indexed keywords

PROTEIN;

ARTICLE; CHEMICAL BOND; ELECTRON; GAMMA RADIATION; IONIZATION; MOLECULE; RADIOLYSIS; RADIOSENSITIVITY;

EID: 0034762067     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.1114     Document Type: Article

References (35)

1. Zur theorie des durchgangs schneller korpuskularstrahlen durch materie
2. Secondary electrons: Average energy loss per ionization
3. 2 in dilute aqueous solution
4. Molecular weights of human prothrombin and thrombin by electron irradiation
5. The functional unit of the arom conjugate in neurospora
6. Radiation-damaged tyrosinase molecules are inactive
7. The influence of low temperature on the radiation sensitivity of enzymes
8. The temperature dependence of radiation sensitivity of large molecules
9. Target analysis of growth factor receptors
10. Molecular mass and volume in radiation target theory
11. Radiation inactivation of the glycoprotein, invertase
12. Effect of environmental conditions on radiation target size analysis
13. + antiport in renal brush border membranes, as estimated by radiation inactivation
14. Molecular weight determinations from radiation inactivation
15. The functional and physical form of mammalian cytochrome c oxidase determined by gel filtration, radiation inactivation, and sedimentation equilibrium analysis
16. Functional unit of the low density lipoprotein receptor of fibroblasts: A 100,000-dalton structure with multiple binding sites
17. +)-ATPase functional and structural molecular size
18. Functional size of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase as determined by radiation inactivation
19. Radiation inactivation of glutamate dehydrogenase hexamer: Lack of energy transfer between subunits
20. Radiation inactivation of human gamma interferon: Cellular activation requires two dimers
21. Effect of subunit interactions on enzymatic activity of glutathione S-transferases: A radiation inactivation study
22. Inactivation mechanism of tetrameric β-galactosidase by γ-rays involves both fragmentation and temperature-dependent denaturation of protomers
23. Radiation effects on the native structure of proteins: Fragmentation without dissociation
24. Radiation target analysis of glycoproteins
25. Radiation target analysis of RNA
26. A monomeric protein in the Golgi membrane catalyzes both N-deacetylation and N-sulfation of heparan sulfate
27. The mathematics of radiation target analyses
28. Analysis of microsomal cholesteryl ester hydrolases by radiation inactivation
29. Characterization of the insulin receptor in its membrane environment by radiation inactivation
30. Structure-function relationships in Escherichia coli transcription termination protein Rho revealed by radiation target analysis
31. Radiation inactivation reveals discrete cation binding sites that modulate dihydropyridine binding sites
32. Radiation inactivation analysis of oligomeric structure of the H,K-ATPase
33. Radiation inactivation analysis of the group A and group C streptococcal hyaluronan synthases reveal the active enzymes are monomeric