Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly

EMBO Reports

Volumn 2, Issue 10, 2001, Pages 933-938

  Chen, L ^a   Shinde, U ^a   Ortolan, T G ^a   Madura, K ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DNA; NUCLEOTIDE; PROTEASOME; UBIQUITIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; EXCISION REPAIR; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CODON; DNA; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FUNGAL PROTEINS; GLUTATHIONE TRANSFERASE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; UBIQUITIN;

EID: 0034762028     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kve203     Document Type: Article

References (28)

1. UBA domains of DNA damage-inducible proteins interact with ubiquitin
2. Dosage suppressors of pds 1 implicate ubiquitin-associated domains in checkpoint control
3. Molecular mechanism of nucleotide excision repair
4. Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr
5. Yeast DNA repair protein RAD23 promotes complex formation between transcription factor TFIIH and DNA damage recognition factor RAD14
6. Reconstitution of yeast nucleotide excision repair with purified Rad proteins, replication protein A, and transcription factor TFIIH
7. Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome
8. Affinity of yeast nucleotide excision repair factor 2, consisting of the Rad4 and Rad23 proteins, for ultraviolet damaged DNA
9. The UBA domain: A sequence motif present in multiple enzyme classes of the ubiquitylation pathway
10. Preferential binding of yeast Rad4-Rad23 complex to damaged DNA
11. Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitylation
12. Pleiotropic growth and proteolytic defects caused by the loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae
13. Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23
14. 3-methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins
15. The Rad23 DNA repair protein is a negative regulator of substrate-linked multi-ubiquitin chain assembly
16. DNA repair genes and proteins of Saccharomyces cerevisiae
17. Rad23 links DNA repair to the ubiquitin/proteasome pathway
18. HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro
19. Rad23 provides a link between the Png1 deglycosylating enzyme and the 26S proteasome in yeast
20. 32P-ubuitin
21. Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome
22. Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23
23. The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover
24. The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function
25. Human immunodeficiency virus Type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair
26. Biochemical and structural analysis of the interaction between the UBA(2) domain on the DNA repair protein HHR23A and HIV-1 Vpr
27. Physical association of ubiquitin ligases and the 26S proteasome
28. Human homologue of yeast Rad23 protein A interacts with p300/Cyclic AMP-responsive element binding (CREB)-binding protein to down-regulate transcriptional activity of p53