A growth factor mixture that significantly enhances angiogenesis in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 2, 2001, Pages 494-500

  Roethy, Wilfred ^a   Fiehn, Eduard ^a   Suehiro, Kotaro ^a   Gu, Anguo ^a   Yi, Geng Hua ^a   Shimizu, Juichiro ^a   Wang, Jie ^a   Zhang, Geping ^a   Ranieri, John ^b   Akella, Rama ^b   Funk, Sarah E ^c   Sage, E Helene ^c   Benedict, James ^b   Burkhoff, Daniel ^a,d  

^a Columbia University ^*  (United States)

^b Sulzer Orthopedics Inc   (United States)

^c HOPE HEART INSTITUTE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; FIBROBLAST GROWTH FACTOR 1; GROWTH FACTOR; MICROSPHERE; OSTEOGENIC PROTEIN 1; OSTEOGENIN; PLACEBO; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

ANGIOCARDIOGRAPHY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE; CHORIOALLANTOIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; COW; DOG; DRUG EFFICACY; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; IN VIVO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SCORING SYSTEM; WESTERN BLOTTING;

ANIMALS; CATTLE; CHORION; CHRONIC DISEASE; CORONARY ANGIOGRAPHY; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GROWTH SUBSTANCES; MASS SPECTROMETRY; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NEOVASCULARIZATION, PATHOLOGIC; QUAIL;

EID: 0034758088     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Vascular development: Cellular and molecular regulation
2. In vivo evaluation of a resorbable osteoinductive composite as a graft substitute for lumbar spinal fusion
3. Mechanisms of angiogenesis and arteriogenesis
4. Angiogenesis in cancer and other diseases
5. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
6. Angiogenic factors
7. Basic fibroblast growth factor and transforming growth factor beta-1: Synergistic mediators of angiogenesis in vitro
8. Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
9. Double blind, placebo controlled trial of recombinant vascular endothelial growth factor - The VIVA trial
10. Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb
11. Measurement of regional myocardial blood flow with multiple colored microspheres
12. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: Results of a phase I randomized, double-blind, placebo-controlled trial
13. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
14. Fibroblast growth factor-2 selectively stimulates angiogenesis of small vessels in arterial tree
15. A novel assay of angiogenesis in the quail chorioallantoic membrane: Stimulation by bFGF and inhibition by angiostatin according to fractal dimension and grid intersection
16. Osteogenic protein-1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor-betal
17. Induction of neoangiogenesis in ischemic myocardium by human growth factors: First clinical results of a new treatment of coronary heart disease
18. Clinical trials in coronary angiogenesis: Issues, problems, consensus. An expert panel summary
19. A model to assess interventions to improve collateral blood flow: Continuous administration of agents into the left coronary artery in dogs
20. Basic fibroblast growth factor enhances myocardial collateral flow in a canine model
21. Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris
22. Randomized, single-blind, placebocontrolled pilot study of angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia
23. Angiogenesis in ischemie heart disease