Distinct mechanisms underlying α1-adrenoceptor and P2x purinoceptor operated ATP release and contraction in the guinea-pig vas deferens

Neurochemical Research

Volumn 26, Issue 8-9, 2001, Pages 951-957

  Sperlágh, Beáta ^a   Illes, Peter ^b   Gerevich, Zoltán ^a   Köfalvi, Attila ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b Unversitaet Leipzig   (Germany)

Author keywords

1 adrenoceptor; ATP; P2x purinoceptor; Release; Vas deferens

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL BLOCKING AGENT; CORBADRINE; LUCIFERASE; LUCIFERIN; NIFEDIPINE; NORADRENALIN; PURINE P2X RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EVOKED RESPONSE; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MALE; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; TEMPERATURE DEPENDENCE; VAS DEFERENS;

ADENOSINE TRIPHOSPHATE; ANIMALS; GUINEA PIGS; MALE; MUSCLE CONTRACTION; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, PURINERGIC P2; VAS DEFERENS;

EID: 0034758043     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012336601854     Document Type: Article

References (33)

1. Noradrenaline and ATP: Cotransmitters and neuromodulators
2. The role of purines in the peripheral nervous system
3. Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors
4. Sympathetic nerve-mediated release of ATP from the guinea-pig vas deferens is unaffected by reserpine
5. Evidence that ATP released from the postsynaptic site by noradrenaline, is involved in mechanical responses of guinea-pig vas deferens: Cascade transmission
6. Release of noradrenaline and ATP by electrical stimulation and nicotine in guinea-pig vas deferens
7. 2-adrenoceptors
8. 14C] ATP
9. Receptor- and carrier-mediated release of ATP of postsynaptic origin: Cascade transmission
10. Existence of ATP-evoked ATP release system in smooth muscles
11. Differential effects of hypothemia on neuronal efflux, release and uptake of noradrenaline
12. Multiple cellular mechanisms mediate the effect of lobeline on the release of norepinephrine
13. 3H]GABA by slices of rat cerebral cortex
14. Different temperature dependence of carrier-mediated (cytoplasmic) and stimulus-evoked (exocytotic) release of transmitter: A simple method to separate the two types of release
15. Extrasynaptic glutamate spillover in the hippocampus: Dependence on temperature and the role of active glutamate uptake
16. Separation of carrier mediated and vesicular release of GABA from rat brain slices
17. Is the neuronal ATP release from guinea-pig vas deferens subject to alpha2-adrenoceptor-mediated modulation?
18. ATP acts as fast neurotransmitter in rat habenula: Neurochemical and enzymecytochemical evidence
19. A possible coupling of postjunctional ATP release and transmitters' receptor stimulation in smooth muscles
20. Characterization of the ATPase released during sympathetic nerve stimulation of the guinea-pig isolated vas deferens
21. Exocytotic release from neuronal cell bodies, dendrites and nerve terminals in sympathetic ganglia of the rat, and its differential regulation
22. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry
23. 21-receptors located on axon terminals
24. ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors
25. Effect of presynaptic P2 receptor stimulation on transmitter release
26. Prejunctional nicotinic receptors involved in facilitation of stimulation-evoked noradrenaline release from the vas deferens of the guinea-pig
27. PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses
28. Design and pharmacology of selective P2-purinoceptor antagonists
29. Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: Suramin-sensitive and suramin-insensitive components in the contractile effect of ATP
30. Characteristics of ecto-ATPase of Xenopus oocytes and the inhibitory actions of suramin on ATP breakdown
31. Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: Functional consequences in rat vas deferens
32. Enhancement of sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens by the novel ecto-ATPase inhibitor ARL 67156
33. Differential cotransmission in sympathetic nerves: Role of frequency of stimulation and prejunctional auto-receptors