The role of ATM in telomere structure and function

Radiation Research

Volumn 156, Issue 5 II, 2001, Pages 642-647

  Pandita, T K ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; TELOMERASE;

ANIMAL CELL; CELL NUCLEUS MATRIX; CHROMATIN STRUCTURE; CHROMOSOME; CONFERENCE PAPER; CONTROLLED STUDY; EXPRESSED SEQUENCE TAG; FIBROBLAST; GENE EXPRESSION; GENE INACTIVATION; GONADAL AGENESIS; HUMAN; HUMAN CELL; IONIZING RADIATION; METABOLISM; MOUSE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TELOMERE; YEAST;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0034757212     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2001)156[0642:troait]2.0.co;2     Document Type: Conference Paper

References (53)

1. The nature of ataxia-telangiectasia: Problems and perspectives
2. Ataxia-telangiectasia: Closer to unraveling the mystery
3. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
4. The complexity of p53 modulation: Emerging patterns from divergent signals
5. Enhanced phosphorylation of p53 by ATM in response to DNA damage
6. 1 arrest
7. ATM associates with and phosphorylates p53: Mapping the region of interaction
8. Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation
9. p53 and ATM: Cell cycle, cell death, and cancer
10. Ionizing radiation activates the ATM kinase throughout the cell cycle
11. Strange bedfellows in even stranger places: The role of ATM in meiotic cells, lymphocytes, tumors and its functional links to p53
12. Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells
13. Fragments of ATM which have dominant-negative or complementing activity
14. Evidence of chromatin defect as a basis of mutagenic sensitivity in head and neck cancer patients with second primaries
15. The mei-41 gene of D. melanogaster is a structural and functional homologue of the human ataxia telangiectasia gene
16. Characterization of ATM expression, localization and associated DNA-dependent protein kinase activity
17. Meiotic telomere distribution and Sertoli cell nuclear architecture is altered in Atto and Atm/p53 deficient mice
18. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
19. Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe
20. Chromosome end association, telomeres and telomerase activity in ataxia telangiectasia cells
21. Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with α-particles simulating radon progeny
22. Accelerated telomere shortening in ataxia telangiectasia
23. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
24. Influence of ATM function on telomere metabolism
25. Altered telomere nuclear matrix interactions and nucleosomal periodicity in cells derived from individuals with ataxia telangiectasia before and after ionizing radiation treatment
26. Phenotypic characterization of ataxia telangiectasia fibroblasts with telomerase-induced extended-life-span
27. 1 checkpoint in telomerase-induced extended-life-span human fibroblasts
28. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
29. The remaking of chromosomes
30. The stability of broken ends of chromosomes of Zea mays
31. Structure and function of telomeres
32. The telomere and telomerase: Nucleic acid-protein complexes acting in a telomere homeostasis system
33. Loss of a yeast telomere: Arrest, recovery and chromosome loss
34. Yeast telomeres exert a position effect on recombination between internal tracts of yeast telomeric DNA
35. Telomeres and senescence: Ending the debate
36. Telomere positional effects and the regulation of cellular senescence
37. TRF1, a mammalian telomeric protein
38. Atm inactivation results in aberrant telomere clustering during meiotic prophase
39. Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
40. p53-and ATM-dependent apoptosis induced by telomeres lacking TRF2
41. Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure
42. Nucleosomal organization of telomere-specific chromatin in rat
43. Unusual chromatin in human telomeres
44. Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner
45. Runaway telomere elongation caused by telomerase RNA gene mutations
46. TRF2 protects human telomeres from end-to-end fusions
47. TIN2, a new regulator of telomere length in human cells
48. Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei
49. Gene gating: A hypothesis
50. Chromatin disruption and modification
51. Structure and function of the core histone N-termini: More than meets the eye
52. Twenty five years of the nucleosome, fundamental particle of the eukaryotic chromosomes
53. Histone acetylation and transcription regulatory mechanisms