Nitration as a mechanism of Na+, K+-ATPase modification during hypoxia in the cerebral cortex of the guinea pig fetus

Neurochemical Research

Volumn 26, Issue 10, 2001, Pages 1163-1169

  Qayyum, Imran ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Enzyme activity; Fetus; Hypoxia; Nitration; Peroxynitrite

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OUABAIN; PEROXYNITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; GUINEA PIG; NITRATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; BLOTTING, WESTERN; CEREBRAL CORTEX; FETUS; GUINEA PIGS; HYPOXIA, BRAIN; MEMBRANE PROTEINS; NA(+)-K(+)-EXCHANGING ATPASE; NITRIC OXIDE SYNTHASE; PEROXYNITROUS ACID; REFERENCE VALUES;

ANIMALIA; CAVIA PORCELLUS; STROPHANTHUS GRATUS; SUS SCROFA;

EID: 0034752431     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012331108641     Document Type: Article

References (56)

1. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests a role as intercellular messenger in the brain
2. Nitric oxide: A radical neurotransmitter in the central nervous system
3. Nitric oxide synthases in mammals
4. Synthesis of nitric oxide in CNS glial cells
5. Glial NO. Normal and pathological roles
6. Inducible nitric oxide synthase in glial cells
7. Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture
8. Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture
9. Induction of nitric oxide synthase in glial cells
10. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures
11. Endothelial cell production of nitrogen oxides in response to interferon in combination with tumor necrosis factor, interleukin-1, or endotoxin
12. In vivo expression of inducible nitric oxide synthase in cerebellar neurons
13. +-ATPase modification following hypoxia in the guinea pig fetus
14. +ATPase in developing fetal guinea pig brain and the effect of maternal hypoxia
15. +, and strophanthidin in vitro
16. Hypoxia-induced generation of nitric oxide free radicals in cerebral cortex of newborn guinea pigs
17. Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet
18. Specific ouabain binding to brain microvessels and choroid plexus
19. Protein measurement with the Folin phenol reagent
20. +-ATPase
21. Modification of modulatory sites of NMDA receptor in the fetal guinea pig brain during development
22. Hypoxia-induced modification of the N-methyl-D-aspartate receptor in the brain of the newborn piglet
23. Effects of 3-(2 carboxypiperazin-4-yl) propyl-1-phosphonic acid (CPP) on NMDA receptor binding characteristics and brain cell membrane function during cerebral hypoxia in newborn piglets
24. NMDA receptor mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus
25. G-Nitro-L-Arginine in newborn piglets
26. Nitric oxidemediated mitochondrial damage in the brain: Mechanisms and implications for neurodegenerative diseases
27. Extensive peroxynitrite activity during progressive stages of central nervous system inflammation
28. Cytosolic and membrane-bound cerebral nitric oxide synthase activity during hypoxia in cortical tissue of newborn piglets
29. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
30. Pretreatment of astrocytes with Interferon-α/β impairs interferon-γ induction of nitric oxide synthase
31. Cellular mechanisms of hypoxic injury in the developing brain
32. Sustained hypoxia-ischemia results in reactive nitrogen and oxygen species production and injury in the fetal rabbit brain
33. The influence of oxygen free radicals on the permeability of the monolayer of cultured brain endothelial cells
34. Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury
35. Role of nitric oxide in neurodegenerative diseases
36. Evidence for peroxidative damage by nitric oxide in experimental chronic cerebral vasospasm
37. Structure activity relationships of peroxynitrite scavengers an approach to nitric oxide neurotoxicity
38. Physiological and pathophysiological roles of nitric oxide in the central nervous system
39. The interactions of nitric oxide with oxygen radicals and scavengers in cerebral ischemic injury
40. Attenuation of rat ischemic brain damage by aged garlic extracts. A possible protecting mechanism as antioxidants
41. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implications for cell death
42. Requirement for superoxide in excitotoxic cell death
43. Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury
44. The double-edged role of nitric oxide in brain function and superoxide anion
45. Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat
46. Immunohistochemical detection of nitrotyrosine in postischemic cerebral cortex in gerbil
47. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
48. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide
49. Oxidative stress during post-hypoxic-ischemic reperfusion in the newborn lamb: The effect of nitric oxide synthesis inhibition
50. Nitric oxide contributes to ireversible membrane dysfunction caused by experimental ischemia in rat hippocampal CA1 neurons
51. Effects of nitric oxide synthase inhibition on brain infarction in SOD-1 transgenic mice following transient focal cerebral ischemia
52. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury. Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
53. The mechanism of free radical generation in brain capillary endothelial cells after anoxia and reoxygenation
54. Nitric oxide neurotoxcity