What is the significance of igf-binding protein-3 proteolysis in the circulation? [1]

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 10, 2001, Pages 5087-5088

  Baxter, R C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 3;

BINDING AFFINITY; CIRCULATION; COMPLEX FORMATION; HORMONE DETERMINATION; HORMONE RELEASE; LETTER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION;

EID: 0034752056     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.86.10.7963-1     Document Type: Letter

References (16)

1. Measurement of intact insulin-like growth factor-binding protein-3 in human plasma using a ligand immunofunctional assay
2. Somatomedins in pregnancy: A cross-sectional study of insulin-like growth factors I and II and somatomedin peptide content in normal human pregnancies
3. Maternal and fetal insulin-like growth factors and their binding proteins in the second and third trimesters of human pregnancy
4. The free form of insulin-like growth factor I increases in circulation during normal human pregnancy
5. Measurement of free form of insulin-like growth factor I in human plasma
6. The presence of cation-dependent proteases for insulin-like growth factor binding proteins does not alter the size distribution of insulin-like growth factors in pregnancy
7. Most of the circulating insulin-like growth factors-I and -II are present in the 150 kDa complex during human pregnancy
8. Insulin-like growth factor binding protein-3 is functionally normal in pregnancy serum
9. High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum
10. Structural determinants for binary and ternary complex formation between insulin-like growth factor-I (IGF-I) and IGF binding protein-3
11. Characterization of the binding defect in insulin-like growth factor binding protein-3 from pregnancy serum
12. Insulin-like growth factor binding protein-3 is functionally altered in pregnancy plasma
13. Altered ligand specificity of proteolysed insulin-like growth factor binding protein-3
14. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: Effects of a pregnancy-associated serum protease activity
15. Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy
16. Insulin-like growth factor (IGF) binding protein-3 in pregnancy serum binds native IGF-I but not iodo-IGF-I