Perineural invasion as a predictor of biochemical outcome following radical prostatectomy for select men with clinically localized prostate cancer

Journal of Urology

Volumn 165, Issue 1, 2001, Pages 126-129

  D'Amico, Anthony V ^a   Wu, Yuehui ^a   Chen, Ming Hui ^a   Nash, Marc ^a   Renshaw, Andrew A ^a   Richie, Jerome P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Outcome and process assessment (health care); Prostate specific antigen; Prostatectomy; Prostatic neoplasms

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; ARTICLE; CANCER STAGING; CONTROLLED STUDY; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; PATIENT SELECTION; PERINEURIUM; PREDICTION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; PROSTATE CARCINOMA; PROSTATECTOMY; TREATMENT OUTCOME; TUMOR LOCALIZATION;

EID: 0034751009     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005392-200101000-00031     Document Type: Article

References (26)

1. Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer. A multi-institutional update
2. Prostatespecific antigen failure despite pathologically organ-confined and margin-negative prostate cancer: The basis for an adjuvant therapy trial
3. Analysis of risk factors for progression in patients with pathologically confined prostate cancers after radical retropubic prostatectomy
4. Stage T1-2 prostate cancer: A multivariate analysis of factors affecting biochemical and clinical failures after radical prostatectomy
5. Equivalent biochemical failure-free survival after external beam radiation therapy or radical prostatectomy in patients with a pretreatment prostate specific antigen of >4-20 ng/ml
6. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer
7. Clinical utility of the percentage of positive prostate biopsies in defining biochemical outcome after radical prostatectomy for patients with clinically localized prostate cancer
8. The role of perineural space invasion in the local spread of prostatic adenocarcinoma
9. Relationship between perineural tumor invasion on needle biopsy and radical prostatectomy capsular penetration in clinical stage B adenocarcinoma of the prostate
10. Systematic biopsies accurately predict extracapsular extension of prostate cancer and persistent/recurrent detectable PSA after radical prostatectomy
11. Prostate cancer staging: Correlation between ultrasound determined tumor contact length and pathologically confirmed extraprostatic extension
12. Prediction of extraprostatic extension of prostate cancer based on needle biopsy findings: Perineural invasion lacks significance on multivariate analysis
13. Perineural invasion on prostate needle biopsy: An independent predictor of final pathologic stage
14. Can perineural invasion on prostate needle biopsy predict prostate specific antigen recurrence after radical prostatectomy?
15. Histologic grading and staging of prostatic carcinoma
16. Free, complexed and total serum prostate specific antigen: The establishment of appropriate reference ranges for their concentrations and ratios
17. A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer
18. Pretreatment nomogram for prostate-specific antigen recurrence after radical prostatectomy or external-beam radiation therapy for clinically localized prostate cancer
19. Selection of men at high risk for disease recurrence for experimental adjuvant therapy following radical prostatectomy
20. Radical prostatectomy for adenocarcinoma of the prostate: The influence of preoperative and pathologic findings on biochemical disease-free outcome
21. Nonparametric estimation from incomplete observations
22. Test for linear trend in proportions and frequencies
23. The role of perineural invasion and other biopsy characteristics as prognostic markers for localized prostate cancer
24. Excision of the neurovascular bundle at radical prostatectomy in cases with perineural invasion on needle biopsy
25. Gleason sums of 7 lose valuable prognostic information in comparison to estimates of % grade 4 and 5 cancer