Antagonism of the discriminative stimulus effects of cocaine at two training doses by dopamine D2-like receptor antagonists

Psychopharmacology

Volumn 158, Issue 2, 2001, Pages 146-153

  Costanza, R M ^a   Barber, D J ^a   Terry, P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Cocaine; D1 like receptor; D2 like receptor; Drug discrimination; Haloperidol; L 741,626; Raclopride; Rat

Indexed keywords

3 [[ (4 CHLOROPHENYL) 4 HYDROXY]PIPERIDIN 1 YL]METHYL 1H INDOLE; 4 (4 CHLOROPHENYL) 1 (1H INDOL 3 YLMETHYL)PIPERIDIN 4 OL; COCAINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; ECOPIPAM; HALOPERIDOL; RACLOPRIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; ATTENUATION; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG SELECTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; COCAINE; CONDITIONING, OPERANT; DISCRIMINATION (PSYCHOLOGY); DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAPERITONEAL; MALE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, DOPAMINE D2;

EID: 0034750870     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100872     Document Type: Article

References (51)

1. 3 receptor ligands
2. The role of monoamine uptake in the discriminative stimulus effects of cocaine and related compounds
3. Assessment of the discriminative stimulus effects of the D3 dopamine antagonist PNU-99194A in rats: Comparison with psychomotor stimulants
4. The dopamine D3 receptor antagonist PNU-99194A fails to block (+)-7-OH-DPAT substitution for D-amphetamine or cocaine
5. Effects of stimulation and blockade of dopamine receptor subtypes on the discriminative stimulus properties of cocaine
6. Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626
7. Discriminative stimulus properties of the putative dopamine D3 receptor agonist, (+)-PD 128907: Role of presynaptic dopamine D2 autoreceptors
8. Generalization of cocaine to the isomers of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine: Effects of training dose
9. Involvement of dopamine uptake in the discriminative stimulus effects of cocaine
10. Lack of discrimination by agonists for D2 and D3 dopamine receptors
11. 2 receptor function in rats
12. Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine
13. Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems
14. Activation of heterologously expressed D3 dopamine receptors: Comparison with D2 dopamine receptors
15. Factors regulating drug cue sensitivity: Limits of discriminability and the role of a progressively decreasing training dose in cocaine-saline discrimination
16. Cocaine cue in rats as it relates to subjective drug effects: A preliminary study
17. The dopamine D4 receptor antagonist L-745,870: Effects in rats discriminating cocaine from saline
18. 1 receptor mediation of the discriminative stimulus properties of SKF 38393
19. Discriminative stimulus effects of a small dose of cocaine
20. The role of dopamine receptor subtypes in the discriminative stimulus effects of amphetamine and cocaine in rats
21. Expression and pharmacological characterisation of the human D3 dopamine receptor
22. Analysis of D2 and D3 receptor-selective ligands in rats trained to discriminate cocaine from saline
23. 2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine
24. The dopamine D1 receptor agonist SKF-82958 serves as a discriminative stimulus in the rat
25. Cocaine as a discriminative cue in rats: Interactions with neuroleptics and other drugs
26. The discriminative stimulus effects of cocaine in pigeons
27. 2 dopamine agonists in rats
28. Effects of N-methyl-D-aspartate antagonists in rats discriminating different doses of cocaine: Comparison with direct and indirect dopamine agonists
29. Cocaine-opioid interactions in groups of rats trained to discriminate different doses of cocaine
30. 1 dopamine antagonist SCH 23390
31. Pharmacological characterisation of the discriminative stimulus effects of cocaine in rhesus monkeys
32. 3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline
33. Antagonism of the discriminative stimulus effects of cocaine with the combination of a dopamine D-1 and D-2 antagonist
34. Pharmacological characterization of the discriminative stimulus effects of GBR 12909
35. The induction of grooming and vacuous chewing by a series of selective D-1 dopamine receptor agonists - Two directions of D1:D2 interaction
36. Drug discrimination training with progressively lowered doses
37. Discriminative characteristics of high and low cocaine administration: Effect of other psychostimulants
38. The D-2 agonist quinpirole releases striatal dopamine in vivo
39. 3 receptors modulate cocaine's reinforcing and discriminative stimulus effects in rhesus monkeys
40. Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys
41. Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys
42. Opioid modulation of the discriminative stimulus effects of cocaine: Comparison of μ, K, and δ agonists in squirrel monkeys discriminating low doses of cocaine
43. Discriminative stimulus effects of cocaine in squirrel monkeys: Involvement of dopamine receptor subtypes
44. Differential antagonism of the effects of dopamine D1 receptor agonists on feeding behavior in the rat
45. Dopaminergic mediation of the discriminative stimulus effects of bupropion in rats
46. Pharmacological characterisation of the novel discriminative stimulus effects of a low dose of cocaine
47. Inability of antipsychotics to antagonize the cueing properties of cocaine in rats
48. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
49. 2 interactions
50. Behavioral effects of selective dopaminergic compounds in rats discriminating cocaine injections