Functional and selective targeting of adenovirus to high-affinity Fcγ receptor I-positive cells by using a bispecific hybrid adapter

Journal of Virology

Volumn 75, Issue 1, 2001, Pages 480-489

  Ebbinghaus, C ^a   Al Jaibaji, A ^a   Operschall, E ^a   Schoffel, A ^a   Peter, I ^a   Greber, U F ^a   Hemmi, S ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BLOCKING ANTIBODY; CD64 ANTIGEN; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY; VIRUS RECEPTOR;

ADENOVIRUS; ANIMAL CELL; ARTICLE; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; VIRUS INFECTION;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, MONOCLONAL; CAPSID; CELLS, CULTURED; GENE THERAPY; HUMANS; IMMUNIZATION; LEUKEMIA, MYELOCYTIC, ACUTE; MICE; MICE, INBRED BALB C; RECEPTORS, IGG; RECEPTORS, VIRUS; RECOMBINANT FUSION PROTEINS; TRANSGENES;

EID: 0034749754     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.1.480-489.2001     Document Type: Article

References (68)

1. A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity
2. Mechanisms of phagocytosis in macrophages
3. Persistent infection with adenovirus types 5 and 6 in lymphoid cells from humans and woolly monkeys
4. The potential for antitumor vaccination in acute myelogenous leukemia
5. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
6. Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types
7. Generation of phagocytic MAK and MAC-DC for therapeutic use: Characterization and in vitro functional properties
8. Functional and structural effects of an Ala to Val mutation in the adenovirus serotype 2 fibre
9. Adenovirus vector infection of chronic lymphocytic leukemia B cells
10. Group D adenoviruses infect primary central nervous system cells more efficiently than those from group C
11. Persistent infection of human adenovirus type 5 in human monocyte cell lines
12. Human adenovirus-host cell interactions: Comparative study with members of sub-groups B and C
13. An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism
14. Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
15. T-helper- and accessory-cell-independent cytotoxic responses to human tumor cells transfected with a B7 retroviral vector
16. Targeted gene delivery by tropism-modified adenoviral vectors
17. Characterization of 911: A new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors
18. Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo
19. Changes in human adenovirus 5 propagated in Burkitt's lymphoma cells
20. Coxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12
21. Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes
22. SV40-transformed simian cells support the replication of early SV40 mutants
23. Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor
24. Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM
25. A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells
26. Studies of monoclonal antibodies specific for major histocompatibility complex products of the rat. I. Production and characterization of monoclonal antibodies
27. The presence of HCAR (human coxsackievirus and adenovirus receptor) is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures
28. Nonpermissivity of human peripheral blood lymphocytes to adenovirus type 2 infection
29. A monoclonal antibody specific for the cellular receptor for the group B coxsack-ieviruses
30. Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
31. Detection of Coxsackie-Adenovirus Receptor (CAR) immunoreactivity in ovarian tumors of epithelial derivation
32. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
33. Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism
34. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
35. High-efficiency transduction of freshly isolated human tumor cells using adenoviral interleukin-2 vectors
36. Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
37. CTLA-4 is a second receptor for the B cell activation antigen B7
38. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12
39. CD80-transfected acute myeloid leukemia cells induce primary allogeneic T-cell responses directed at patient specific minor histocompatibility antigens and leukemia-associated antigens
40. Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cells
41. Antileukemic HLA-restricted T-cell clones generated with naturally processed peptides eluted from acute myeloblastic leukemia blasts
42. Comparative analysis of adenovirus fiber-cell interaction: Adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment
43. Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae
44. Consensus protocol for the flow cytometric immunophenotyping of hematopoietic malignancies. Working Group on Flow Cytometry and Image Analysis
45. Activation of the alpha 4 beta 1 integrin through the beta 1 subunit induces recognition of the RGDS sequence in fibronectin
46. HLA-Cw3 expression on porcine endothelial cells protects against xenogeneic cytotoxicity mediated by a subset of human NK cells
47. Adenovirus types 11p and 35p show high binding efficiencies for committed hematopoietic cell lines and are infective to these cell lines
48. Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector
49. Interaction of human adenovirus serotype 2 with human lymphoid cells
50. Cell-specific viral targeting mediated by a soluble retroviral receptor-ligand fusion protein
51. Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein
52. Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector
53. Expression of the adenovirus receptor and its interaction with the fiber knob
54. HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
55. Rapid production of interleukin-2-secreting tumor cells by herpes simplex virus-mediated gene transfer: Implications for autologous vaccine production
56. Human IgG Fc receptor heterogeneity: Molecular aspects and clinical implications
57. Infectious entry pathway of adenovirus type 2
58. Characterization of an arsenic-sensitive monoblast leukemia cell line SigM5
59. Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia
60. Adenovirus internalization and infection require dynamin
61. The 'adenobody' approach to viral targeting: Specific and enhanced adenoviral gene delivery
62. Differential efficacy of adenoviral mediated gene transfer into cells from hematological cell lines and fresh hematological malignancies
63. Targeted adenovirus-mediated gene delivery to T cells via CD3
64. Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment
65. Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types
66. Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies
67. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins
68. Incorporation of adenovirus into a ligand-based DNA carrier system results in retention of original receptor specificity and enhances targeted gene expression