Pituitary hormone mRNA in null cell adenomas and oncocytomas by in situ hybridization comparison with immunohistochemical and clinical data

Pathology Research and Practice

Volumn 197, Issue 10, 2001, Pages 663-669

  Schmid, Michael ^a   Münscher, Adrian ^a   Saeger, Wolfgang ^a,c   Schreiber, Silke ^a   Lüdecke, Dieter K ^b  

^a Marienkrankenhaus Hamburg   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Marienkrankenhaus   (Germany)

Author keywords

Adenoma; Hormone content; Inactive adenomas; mRNA; Pituitary

Indexed keywords

CORTICOTROPIN; DIGOXIGENIN; FOLLITROPIN; GROWTH HORMONE; HYPOPHYSIS HORMONE; ISOTOPE; KI 67 ANTIGEN; LUTEINIZING HORMONE; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KI 67; PROLACTIN; RECOMBINANT FOLLITROPIN; THYROTROPIN;

ADULT; AGED; ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; CLINICAL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HORMONE SYNTHESIS; HUMAN; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; MALE; NULL CELL; OLIGONUCLEOTIDE PROBE; ONCOCYTOMA; SIGNAL DETECTION; STEM CELL;

EID: 0034749747     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1078/0344-0338-00143     Document Type: Article

References (34)

1. Tumors of the pituitary gland
2. In vitro studies of human pituitary adenomas
3. Human pituitary null cell adenomas and oncocytomas in vitro: Effects of adenohypophysiotropic hormones and gonadal steroids on hormone secretion and tumor cell morphology
4. Gonadotropin secretion in vitro by human pituitary null cell adenomas and oncocytomas
5. Clinically non-functioning human pituitary adenomas
6. HGH, PRL and beta HCG/beta LH gene expression in clinically inactive pituitary adenomas detected by in situ hybridization
7. Hormone production in clinically nonfunctioning pituitary adenomas
8. Contribution of immunohistochemistry, electron microscopy, and cell culture to the characterization of nonfunctioning pituitary adenomas: A study of 40 cases
9. Recognition of gonadotroph adenomas in women
10. Detection of messenger RNA using a digoxigenin end labelled oligodeoxynucleotide probe
11. Null cell adenomas and oncocytomas of the pituitary gland
12. A novel type of pituitary adenoma: Morphological features and clinical correlations
13. Glycoprotein hormone genes are expressed in clinically non-functioning pituitary adenomas
14. In situ hybridization histochemistry of mRNAs for hormones and chromogranins in normal pituitary tissue and pituitary adenoma
15. Silent somatotroph adenomas of the human pituitary. A morphologic study of three cases including immunocytochemistry, electron microscopy, in vitro examination, and in situ hybridization
16. Quantitative in-situ hybridization histochemistry studies on growth hormone (GH) gene expression in acromegalic somatotrophs: Effects of somatostatin, GH-releasing factor and cortisol
17. The pathogenesis of pituitary adenomas
18. Reassessment of the role of radiation therapy in the treatment of endocrine-inactive pituitary macroadenomas
19. Analysis of human pituitary tumors by in situ hybridization
20. Analysis of endocrine active and clinically silent corticotroph adenomas by in situ hybridization
21. In situ hybridization in the study of pituitary tissues
22. Analysis of pituitary hormones and chromogranin A mRNAs in null cell adenomas, oncocytomas, and gonadotroph adenomas by in situ hybridization
23. HGH, PRL and ACTH gene expression in clinically nonfunctioning adenomas detected with nonisotopic in situ hybridization method
24. GH-, PRL-, POMC-, β-TSH-, β-LH-, β-FSH-mRNA in gonadotroph adenomas of the pituitary by in situ hybridization in comparison with immunostaining and clinical data
25. Non-isotopic in situ hybridization with digoxigenin and alkaline phosphatase labelled oligodeoxynucleotide probes. Applications in pituitary gland
26. Immunohistochemical demonstration of oncocytes in nongonadotrophic pituitary adenomas
27. Immunocytochemical demonstration of oncocytes in normal adenohypophysis
28. Immunocytochemical study of pituitary oncocytic adenomas
29. In situ hybridization for different mRNA in GH-secreting and in inactive pituitary adenomas
30. Detection of mRNA of prolactin and ACTH in clinically nonfunctioning pituitary adenomas
31. Proliferation markers in different types of clinically non-secreting pituitary adenomas
32. Detection of growth hormone, prolactin and human beta-chorionic gonadotropin mRNA in growth hormone-secreting pituitary adenomas and in prolactin-secreting pituitary adenomas by in situ hybridization using a method
33. Oncocytomas and null cell adenomas of the human pituitary: Morphometric and in vitro functional comparison
34. Morphological study of clinically nonsecreting pituitary adenomas in patients under 40 years of age