In vitro cytotoxicity of the LDE: Daunorubicin complex in acute myelogenous leukemia blast cells

Brazilian Journal of Medical and Biological Research

Volumn 34, Issue 10, 2001, Pages 1257-1263

  Dorlhiac Llacer, P E ^a   Marquezini, M V ^a   Toffoletto, O ^a   Carneiro, R C G ^a   Maranhao R C ^a   Chamone, D A F ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acute myelogenous leukemia; Cytotoxicity; Daunorubicin; LDE complex; Low density lipoprotein; RT PCR

Indexed keywords

ANTINEOPLASTIC AGENT; APOLIPOPROTEIN E; DAUNORUBICIN; DRUG CARRIER; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; BLAST CELL; BONE MARROW CELL; CANCER CELL; CELL KILLING; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG SYNTHESIS; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MICROEMULSION; PROTECTION; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034749602     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2001001000004     Document Type: Article

References (22)

1. A receptor-mediated pathway for cholesterol homeostasis
2. Molecular biology of human apolipoproteins B and E and associated diseases of lipoprotein metabolism
3. Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation
4. Low density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells
5. Targeted killing of cultured cells by receptor-dependent photosensitization
6. Preparation and interaction of a low-density lipoprotein: Daunorubicin complex with P388 leukemic cells
7. Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo study of a drug-lipoprotein complex
8. Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells
9. 4-octadecyl-1 β-D-arabinofuranosylcytosine in Daudi lymphoma cells
10. Treatment of cancer patients with a low-density-lipoprotein delivery vehicle containing a cytotoxic drug
11. Microemulsion of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein
12. Metabolic behavior in rats of a nonprotein microemulsion resembling low-density lipoprotein
13. Significance of the low density lipoprotein (LDL) receptor pathway for the in vitro accumulation of AD-32 incorporated into LDL in normal and leukemic white blood cells
14. Lipoprotein receptors in acute myelogenous leukemia: Failure to detect increased low-density lipoprotein (LDL) receptor numbers in cell membranes despite increased cellular LDL degradation
15. Plasma kinetic behavior in hyperlipidemic subjects of a lipidic microemulsion that binds to low density lipoprotein receptors
16. Plasma kinetics and biodistribution of a lipid emulsion resembling low-density lipoprotein in patients with acute leukemia
17. Heterogeneity in the cellular commitment of a human leukemic cell line: K562
18. The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia
19. N-Acetyl-p-benzoquinone imine: A cytochrome P-450 mediated oxidation product of acetaminophen
20. Delivery of aclacinomycin A to human glioma cells in vitro by the low-density lipoprotein pathway
21. Low density lipoprotein uptake: Holoparticle and cholesteryl ester selective uptake