Interleukin-6 stimulates thyrotropin receptor expression in human orbital preadipocyte fibroblasts from patients with Graves' ophthalmopathy

Thyroid

Volumn 11, Issue 10, 2001, Pages 929-934

  Jyonouchi, S C ^a   Valyasevi, R W ^a   Harteneck, D A ^a   Dutton, C M ^a   Bahn, R S ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; CYCLIC AMP; CYTOKINE; INTERLEUKIN 1ALPHA; INTERLEUKIN 4; INTERLEUKIN 6; THYROTROPIN RECEPTOR;

ARTICLE; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL STIMULATION; CLINICAL ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; EYE DISEASE; FIBROBLAST; GENE EXPRESSION; GRAVES DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; PATHOGENESIS; PRIORITY JOURNAL; PROADIPOCYTE;

EID: 0034748260     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/105072501753210984     Document Type: Article

References (24)

1. Detection of TSH receptor RNA in cultured fibroblasts from patients with Graves' ophthalmopathy and pretibial dermopathy
2. Expression of thyrotropin-receptor mRNA in healthy and Graves' retro-orbital tissue
3. The thyrotropin receptor in thyroid eye disease
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6. Immunohistochemical and ultrastructural studies on the exenterated orbital tissues of a patient with Graves' disease
7. Glycosaminoglycans in thyroid eye disease
8. Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture
9. Differentiation of human orbital preadipocyte fibroblasts induces expression of functional thyrotropin receptor
10. The effect of IFN-γ TNF-α, tgf-β on adipogenesis and expression of thyrotropin receptor in human orbital preadipocyte fibroblasts
11. Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
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16. High circulating IL-6 levels in Graves' ophthalmopathy
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