Polylysine-induced 2H NMR-observable domains in phosphatidylserine/phosphatidylcholine lipid bilayers

Biophysical Journal

Volumn 81, Issue 6, 2001, Pages 3346-3362

  Franzin, Carla M ^a   Macdonald, Peter M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLSERINE; CHOLINE; DEUTERIUM; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; POLYLYSINE; PROTON; UNCLASSIFIED DRUG; ION; LYSINE; PHOSPHATIDYLGLYCEROL;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; ENERGY; HYDROPHOBICITY; IONIC STRENGTH; LIPID BILAYER; MEMBRANE STRUCTURE; MEMBRANE VESICLE; MOLECULAR INTERACTION; PH; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN TERTIARY STRUCTURE;

HYDROGEN-ION CONCENTRATION; IONS; LIPID BILAYERS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; PHOSPHATIDYLSERINES; POLYLYSINE; PROTEIN STRUCTURE, TERTIARY;

EID: 0034747216     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75968-1     Document Type: Article

References (77)

1. Binding of small basic peptides to membranes containing acidic lipids: Theoretical models and experimental results
2. Melittin binding to mixed phosphatidylglycerol/phosphatidylcholine membranes
3. 2H-NMR studies of a fragment of PMP1, a regulatory subunit associated with the yeast plasma membrane H(+)-ATPase: Conformational properties and lipid-peptide interactions
4. Direct determination of the oriented sample NMR-spectrum from the powder spectrum for systems with local axial symmetry
5. Amino acid sequence of the encephalitogenic basic protein from human myelin
6. Protective effect of lipid surfaces against pressure-induced conformational changes of poly(L-lysine)
7. Investigation of polylysine-dipalmitoylphosphatidylglycerol interactions in model membranes
8. Membrane electrostatics
9. Charge density-dependent strength of hydration and biological structure
10. 2H NMR
11. Surface charge dependence of polyelectrolyte-induced domain size and composition in lipid bilayer membranes
12. Lipid polymorphism and the functional role of lipids in biological membranes
13. Fluorescence studies of membrane dynamics and heterogeneity
14. Quadrupolar echo resonance spectroscopy in ordered hydrocarbon chains
15. Binding of basic peptides to membranes produces lateral domains enriched in the acidic lipids phosphatidylserine and phosphatidylinositol 4,5 bisphosphate: An electrostatic model and experimental results
16. Molecular aspects of the bilayer stabilization induced by poly(L-lysines) or varying size in cardiolipin liposomes
17. The structure and history of an ancient protein
18. The variety of cell surface membrane domains
19. Basic Al protein of the myelin membrane: The complete amino acid sequence
20. Characterization and formation of lipid domains in vesicles and erythrocyte membranes
21. MARCKS produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains
22. Direct detection of domains in phospholipid bilayers by grazing incidence diffraction of neutrons and atomic force microscopy
23. Structure of macromolecular aggregates. II. Construction of model membranes from phospholipids and polypeptides
24. Binding of polylysine to charged bilayer membranes: Molecular organization of a lipid/peptide complex
25. Monte Carlo simulation of lipid mixtures: Finding phase separation
26. Nonideal mixing of phosphatidylserine and phosphatidylcholine in the fluid lamellar phase
27. Signal transduction in neutrophil membrane domains
28. Rotational and translational diffusion in membranes measured by fluorescence and phosphorescence methods
29. Binding of peptides with basic residues to membranes containing acidic phospholipids
30. Phosphorylation, high ionic-strength, and calmodulin reverse the binding of MARCKS to phospholipid-vesicles
31. Lipid dynamics and peripheral interactions of proteins with membrane surfaces
32. Spin-label electron spin resonance studies on the interactions of lysine peptides with phospholipid membranes
33. 2H-nuclearmagnetic-resonance relaxation
34. Study of the effect of poly(L lysine) on phosphatidic acid and phosphatidylcholine/phosphatidic acid bilayers by Raman spectroscopy
35. 2H NMR and Raman study of polylysine-phosphatidic acid systems
36. Formation of membrane domains created during the budding of vesicular stomatitis virus: A model for selective lipid and protein sorting in biological membranes
37. Polyelectrolyte-induced domains in lipid bilayer membranes: The deuterium NMR perspective
38. 2H NMR and polyelectrolyte-induced domains in lipid bilayers
39. Response of the phosphatidylcholine head group to membrane surface charge in ternary mixtures of neutral, cationic and anionic lipids: A deuterium NMR study
40. Resolving the two monolayers of a lipid bilayer in giant unilamellar vesicles using deuterium nuclear magnetic resonance
41. Lipid demixing and protein-protein interactions in the adsorption of charged proteins on mixed membranes
42. The myristoyl-electrostatic switch: A modulator of reversible protein-membrane interactions
43. Vibrational spectroscopic studies of lipid domains in biomembranes and model systems
44. 2H NMR
45. 2H nuclear magnetic resonance
46. 2H-NMR
47. Polyelectrolyte molecular weight and electrostatically-induced domains in lipid bilayer membranes
48. Modulation of melittin-induced lysis by surface-charge density of membranes
49. Peptides that mimic the pseudosubstrate region of protein kinase C bind to acidic lipids in membranes
50. Experimental study of the porosity of loose stacks of stiff cylindrical fibres: Influence of the aspect ratio of fibres
51. The effects of shape on the interaction of colloidal particles
52. Cholesterol dependent recruitment of di22:6-PC by a G protein-coupled receptor into lateral domains
53. Obtaining high-fidelity spin-1/2 powder spectra in anisotropic media: Phase-cycled Hahn echo spectroscopy
54. Lateral inhomogeneous lipid membranes: Theoretical aspects
55. 2H-NMR study
56. 31P NMR study of pentalysine with headgroup deuterated phosphatidylcholine and phosphatidylserine
57. Conformational changes of phospholipid headgroups induced by a cationic integral membrane peptide as seen by deuterium magnetic resonance
58. 2H NMR
59. Electric charge effects on phospholipid headgroups: Phosphatidylcholine in mixtures with cationic and anionic amphiphiles
60. 31P nuclear magnetic resonance and the head group structure of phospholipids in membranes
61. Phospholipid head groups as sensors of electric charge in membranes
62. De-Pake-ing of NMR spectra
63. Detection of lipid domains in docosahexaenoic acid-rich bilayers by acyl chain-specific FRET probes
64. Membrane association of myrsistoylated alanine-rich protein kinase C substrate (MARCKS) protein
65. Structure and phase behaviour of dimyristoylphosphatidic acid/poly(L-lysine) systems
66. Lipid solvation of cytochrome c oxidase: Deuterium, nitrogen, and phosphorus-31 nuclear magnetic resonance studies on the phosphocholine head-groups and on cis-unsaturated fatty acyl chains
67. Structure and phase behaviour of dimyristoylphosphatidic acid/poly(L-lysine) systems
68. Biological membrane domains: Functional significance
69. Lipid domains and lipid/protein interactions in biological membranes
70. a values for phosphatidylserine and phosphatidylethanolamine in phosphatidylcholine host bilayers
71. Translational diffusion in phase-separated lipid bilayer domains
72. Interactions controlling the membrane binding of basic protein domains: Phenylalanine and the attachment of the myristoylated alanine-rich c-kinase substrate protein to interfaces
73. The α-helix as an electric macro-dipole
74. Bilayers of phosphatidylglycerol: A deuterium and phosphorus nuclear magnetic resonance study of the head-group region
75. Lipid domains: The parable of the blind men and the elephant
76. +)-ATPase-rich membranes from Torpedo marmota electric organ evidenced by spin-spin interactions between spin-labelled phospholipids