A role for endogenous TGFα and associated signaling pathways in the differentiation of lens fiber cells

Journal of Cellular Physiology

Volumn 186, Issue 2, 2001, Pages 288-297

  Chen, Fang ^a   Mrock, Linda K ^a   Ireland, Mark E ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR ALPHA; 4 ((3 BROMOPHENYL)AMINO) 6,7 DIMETHOXYQUINAZOLINE; 4-((3-BROMOPHENYL)AMINO)-6,7-DIMETHOXYQUINAZOLINE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EYE PROTEIN; FILENSIN; INTERMEDIATE FILAMENT PROTEIN; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE 1; QUINAZOLINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHICKEN; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; LENS EPITHELIUM; LENS FIBER; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; LENS; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CHICKENS; CYCLIC AMP; ENZYME INHIBITORS; EYE PROTEINS; INTERMEDIATE FILAMENT PROTEINS; ISOPROTERENOL; LENS, CRYSTALLINE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; QUINAZOLINES; RECEPTOR CROSS-TALK; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0034746742     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4652(200002)186:2<288::AID-JCP1031>3.0.CO;2-H     Document Type: Article

References (57)

1. Human aqueous humor catecholamines
2. PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner
3. A new method for study of normal lens development in vitro using pulsatile delivery of PDGF or EGF in HL-1 serum-free medium
4. Expression of insulin-like growth factor I in developing lens is compartmentalized
5. In vitro studies on the assembly properties of the lens proteins CP49, CP115: Coassembly with α-crystallin but not with vimentin
6. FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens
7. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
8. The physiology of transforming growth factor-α
9. Growth inhibitory activities in avascular tissues are recognized by anti-transforming growth factor β antibodies
10. Differential activation of ErbB receptors in the rat olfactory mucosa by transforming growth factor-alpha and epidermal growth factor in vivo
11. A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
12. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
13. The role of fibroblast growth factor and epidermal growth factor in the proliferative response of the corneal and lens epithelium
14. Filensin and phakinin form a novel type of beaded intermediate filaments and coassemble de novo in cultured cells
15. Bovine filensin possesses primary and secondary structure similarity to intermediate filament proteins
16. Quantification of proteins dissolved in an electrophoresis sample buffer
17. Gene structure and cDNA sequence identify the beaded filament protein CP49 as a highly divergent type I intermediate filament protein
18. Receptors for insulin and epidermal growth factor: Relation to synthesis of DNA in cultured rabbit lens epithelium
19. A family of lens fiber specific proteins
20. Lens beta-adrenergic receptors. Functional coupling to adenylate cyclase and photoaffinity labeling
21. Differentiation of chick lens epithelial cells: Involvement of the epidermal growth factor receptor and endogenous ligand
22. β-adrenergic mechanisms affect cell division and differentiation in cultured chick lens epithelial cells
23. Cell-cell interactions affect the accumulation of a cytokeratin-like protein during lens fiber differentiation
24. Quantification and regulation of mRNAs encoding beaded filament proteins in the chick lens
25. Up-regulation of novel intermediate filament proteins in primary fiber cells: An indicator of all vertebrate lens fiber differentiation?
26. Cell shape-mediated growth control of lens epithelial cells grown in culture
27. Kinetics of cyclic AMP-dependent accumulation of novel intermediate filament proteins in cultured chick lens cells
28. Induction and maintenance of differentiation of rat lens epithelium by FGF-2, insulin and IGF-1
29. Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells
30. Synergism between temporally distinct growth factors: bFGF, insulin and lens cell differentiation
31. IGF enhancement of FGF-induced fibre differentiation and DNA synthesis in lens explants
32. Localization of acidic fibroblast growth factor, basic fibroblast growth factor, and heparan sulphate proteoglycan in rat lens: Implications for lens polarity and growth patterns
33. Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth
34. Identification and functional analysis of mouse lens filensin gene promoter
35. Nuetonal defects and delayed wound healing in mice lacking fibroblast growth factor 2
36. Epidermal growth factor in human aqueous humor
37. Immunohistochemical localization of TGF-β1, TGF-β2 and TGF-β3 in mouse embryo: Expression patterns suggest multiple roles during embryonic development
38. Identification of receptor tyrosine kinases in the embryonic chicken lens
39. Expression of transforming growth factor β in embryonic avian lens coincides with the presence of mitochondria
40. The beaded filament of the eye lens: An unexpected key to intermediate filament structure and function
41. Chicken filensin: A lens fiber cell protein that exhibits sequence similarity to intermediate filament proteins
42. Lens-specific expression of PDGF-A alters lens growth and differentiation
43. TGFα can act as a chemoattractant to perioptic mesenchymal cells in developing mouse eyes
44. Specificity within the EGF famfiy/ErbB receptor family signaling network
45. Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice
46. TGFβ2 knockout mice have multiple developmental defects that are nonoverlapping with other TGFβ knockout phenotypes
47. Acidic and basic FGF in ocular media and lens: Implications for lens polarity and growth patterns
48. Strain-dependent epithelial defects in mice lacking the EGF receptor
49. Disruption of lens fiber cell differentiation and survival at multiple stages by region-specific expression of truncated FGF receptors
50. Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens
51. Radioimmunoassay of epidermal growth factor in human lenses at various stages of development of cataract
52. Electrophoretic transfer of proteins from polyacrylamide gel to nitrocellulose paper: Procedures and some applications
53. EGF receptor
54. Hepatocyte growth factor, keratinocyte growth factor, and other growth factor-receptor systems in the lens
55. The effect of transforming growth factor-alpha (TGF-α) on rabbit and primate lens epithelial cells in vitro
56. Cellular and molecular features of lens differentiation: A review of recent advances
57. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation