Blockade of α2-adrenergic receptors markedly potentiates glutamate-evoked activity of locus coeruleus neurons

International Journal of Neuroscience

Volumn 106, Issue 1-2, 2001, Pages 95-99

  Simson, P E ^a  

^a MIAMI UNIVERSITY   (United States)

Author keywords

Glutamate; Locus coeruleus; Norepinephrine; 2

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; GLUTAMIC ACID;

ANIMAL; ARTICLE; DRUG EFFECT; LOCUS CERULEUS; MALE; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; GLUTAMIC ACID; LOCUS COERULEUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2;

EID: 0034746339     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.3109/00207450109149740     Document Type: Article

References (7)

1. Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli
2. Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal
3. Ethanol inhibits NMDA-evoked electrophysiological activity in vivo
4. 2 receptor blockade increases responsiveness of locus coeruleus neurons to excitatory stimulation
5. Altered activity of the locus coeruleus in an animal model of depression
6. Peripheral, but not local or intracerebroventricular, administration of benzodiazepines attenuates evoked activity of locus coeruleus neurons
7. 2 receptors: Light microscopic autoradiographic localization