AT1 receptor antagonist combats oxidative stress and restores nitric oxide signaling in the SHR

Kidney International

Volumn 59, Issue 4, 2001, Pages 1257-1263

  Welch, W J ^a   Wilcox, C S ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

7 nitroindazole; Candesartan; Glomerular filtration rate; Hypertension; Oxygen radicals; Reactive oxygen species; Tempol; Tubuloglomerular feedback

Indexed keywords

7 NITROINDAZOLE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; CANDESARTAN; HYDRALAZINE; HYDROCHLOROTHIAZIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; RESERPINE; SUPEROXIDE DISMUTASE; TEMPOL; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN RECEPTOR; ANTIHYPERTENSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; TETRAZOLE DERIVATIVE; TRANSFORMING GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; GLOMERULUS; GLOMERULUS FILTRATION RATE; JUXTAGLOMERULAR APPARATUS; KIDNEY TUBULE; MACULA DENSA; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RAT STRAIN; RENOVASCULAR HYPERTENSION; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; TREATMENT OUTCOME; ANIMAL; BLOOD PRESSURE; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; HYPERTENSION; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; WISTAR KYOTO RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BLOOD PRESSURE; DRUG COMBINATIONS; FEEDBACK; HYDRALAZINE; HYDROCHLOROTHIAZIDE; HYPERTENSION; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TUBULES; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; RESERPINE; SIGNAL TRANSDUCTION; TETRAZOLES; TRANSFORMING GROWTH FACTORS;

EID: 0034744954     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.0590041257.x     Document Type: Article

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