Nongenomic vitamin D3 analogs activating ERK2 in HL-60 cells show that retinoic acid-induced differentiation and cell cycle arrest require early concurrent MAPK and RAR and RXR activation [2]

In Vitro Cellular and Developmental Biology - Animal

Volumn 37, Issue 2, 2001, Pages 93-99

  Yen, A ^a   Norman, A W ^b   Varvayanis, S ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLECALCIFEROL; DRUG DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; TRANSCRIPTION FACTOR; COLECALCIFEROL DERIVATIVE;

CELL CYCLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; KINETICS; LETTER; METABOLISM; PHYSIOLOGY; CELL ACTIVATION; CELL CYCLE G0 PHASE; CELL DENSITY; CELL GROWTH; CELL LINE; HUMAN CELL; SIGNAL TRANSDUCTION;

CELL CYCLE; CELL DIFFERENTIATION; CHOLECALCIFEROL; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; TRANSCRIPTION FACTORS; TRETINOIN;

EID: 0034744592     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1290/1071-2690(2001)037<0093:NVDAAE>2.0.CO;2     Document Type: Letter

References (18)

1. Retinoic acid-induced blr1 expression promotes ERK2 activation and cell differentiation in HL-60 cells
2. Retinoic acid-induced BLR1 expression requires RARα, RXR, and MAPK activation and uses ERK2 but not JNK/SAPK to accelerate cell differentiation
3. Myeloid differentiation and RB phosphorylation changes in HL-60 cells induced by RAR and RXR-selective retinoic acid analogs
4. Continuous growth and differentiation of human myeloid leukemic cells in suspension culture
5. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia
6. Retinoic acid treatment of acute promyelocytic leukemia: In vitro and in vivo observations
7. Retinoids and vertebrate development
8. Retinoic acid causes MEK-dependent RAF phosphorylation dependent on RARα plus RXR activation
9. 3-26,23-lactone analogs antagonize differentiation of human leukemia cells (HL-60 cells) but not of human acute promyelocytic leukemia cells (NB4 cells)
10. 3
11. 3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses
12. Vitamin A in human nutrition
13. Stimulation of phosphorylation of mitogen-activated protein kinase by 1α,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: A structure function study
14. HL-60 cells as a model of growth control and differentiation: The significance of variant cells
15. Cell cycle dependence of calmodulin levels during HL-60 proliferation ands myeloid differentiation: No changes during pre-commitment
16. Control of HL-60 cell differentiation lineage specificity: A late event occurring after precommitment
17. Dependence of HL-60 myeloid cell differentiation on continuous and split retinoic acid exposures: Precommitment memory associated with altered nuclear structure
18. Retinoic acid induces mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest