FcεRI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells

Seminars in Immunology

Volumn 13, Issue 2, 2001, Pages 99-105

  Holowka, David ^a   Baird, Barbara ^a  

^a Cornell University ^*  (United States)

Author keywords

IgE receptor; Lipid rafts; Membrane domains; Plasma membrane structure

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN E RECEPTOR; PROTEIN KINASE P60;

ARTICLE; CELL HETEROGENEITY; CELL MEMBRANE; CYTOSKELETON; HEMATOPOIETIC CELL; LIPID MEMBRANE; MEMBRANE STRUCTURE; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; REVIEW;

ANIMALS; HEMATOPOIETIC STEM CELLS; MEMBRANE MICRODOMAINS; RECEPTORS, IGE; SIGNAL TRANSDUCTION;

EID: 0034744443     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.2000.0301     Document Type: Article

References (79)

1. The fluid mosaic model of the structure of cell membranes
2. Redistribution and pinocytosis of lymphocyte surface immunoglobulin molecules induced by anti-immunoglobulin antibody
3. Receptor mobility and receptor-cytoplasmic interactions in lymphocytes
4. Static and dynamic lipid asymmetry in cell membranes
5. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics
6. Brownian motion in biological membranes
7. Translational diffusion of acetylcholine receptor (monomeric and dimeric forms) of Torpedo marmorata reconstituted into phospholipid bilayers studied by fluorescence recovery after photobleaching
8. Association of spectrin with its membrane attachment site restricts lateral mobility of human erthtrocyte integral membrane proteins
9. Lateral mobility of integral membrane proteins is increased in spherocytic erythrocytes
10. Lipid microdomains in cell surface membranes
11. Molecular crowding on the cell surface
12. Single-particle tracking: Applications to membrane dynamics
13. Mobility and cytoskeletal interactions of cell adhesion receptors
14. Biomembrane fluidity: The concept and its development
15. Phase equilibria in binary mixtures of phosphatidylcholine and cholesterol
16. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
17. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases
18. Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior
19. On the origin of sphingolipid/cholesterol-rich detergent-insoluble cell membranes: Physiological concentrations of cholesterol and sphingolipid induce formation of a detergent-insoluble, liquid-ordered lipid phase in model membranes
20. Reconstitution of "lipid rafts" in model membranes
21. Caveolae: Where incoming and outgoing messengers meet
22. Caveolae, caveolin and caveolin-rich membrane domains: A signalling hypothesis
23. The fine structure of blood capillaries
24. The caveolae membrane system
25. Functional rafts in cell membranes
26. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment
27. Selective solubilization of proteins and phospholipids from red blood cell membranes by non-ionic detergents
28. Protein and lipid composition of the detergent insoluble plasma membrane matrix of lymphoid cells
29. Lipid domain structure of the plasma membrane revealed by patching of membrane components
30. Interactions between Fc(epsilon)RI and lipid raft components are regulated by the actin cytoskeleton
31. Antigen-mediated IgE receptor aggregation and signaling: A window on cell surface structure and dynamics
32. lyn to detergent-resistant membrane domains accompanies cellular signaling
33. Dissociation of the receptor for immunoglobulin E in mild detergents
34. Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation
35. Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains
36. Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcεRI and their association with detergent-resistant membranes
37. Structural aspects of the association of FcεRI with detergent-resistant membranes
38. An IgE-dependent secretory response of mast cells can be induced by a glycosphingolipid-specific monoclonal antibody
39. Compartmentalized IgE receptor-mediated signal transduction in living cells
40. Membrane and cytoskeletal changes associated with IgE-mediated serotonin release from rat basophilic leukemia cells
41. Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization
42. Observing FcepsilonRI signaling from the inside of the mast cell membrane
43. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
44. Imaging antigen recognition by naive CD4+ T cells: Compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
45. Nocodazde inhibits signal transduction by the T cell antigen receptor
46. Making the T cell receptor go the distance: A topological view of T cell activation
47. Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
48. Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes
49. Gamma-chain dependent recruitment of tyrosine kinases to membrane rafts by the human IgA receptor Fc alpha R
50. Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: Accumulation of actin regulated by local tyrosine phosphorylation
51. Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases
52. lyn protein-tyrosine kinase
53. Transmembrane signaling by the high-affinity IgE receptor on membrane preparations
54. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
55. Initiation and processing of signals from the B cell antigen receptor
56. It's spring, and thoughts turn to...allergies
57. The high affinity IgE receptor (FcεRI): From physiology to pathology
58. Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity
59. Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor
60. The unique domain as the site on Lyn kinase for its constitutive association with the high affinity receptor for IgE
61. Structure-function relationships in the mast cell high affinity receptor for IgE. Role of the cytoplasmic domains and of the beta subunit
62. The FcεRIβ subunit functions as an amplifier of FcεRIγ-mediated cell activation signals
63. Allergy-associated FcRβ is a molecular amplifier of IgE- and IgG-mediated in vivo responses
64. Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells
65. The regulation of antigen receptor signaling by protein tyrosine phosphatases: A hole in the story
66. CD45 and Src-family kinases: And now for something completely different
67. lck associated with glycolipid-enriched membrane domains
68. The role of lipid rafts in T cell antigen receptor (TCR) signalling
69. CD45-deficient RBL-2H3 cells. Cellular response to Fc epsilon R- and ionophore-induced stimulation
70. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
71. Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling
72. Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes
73. Regulation of the Ca2+-inhibitable adenylyl cyclase type VI by capacitative Ca2+ entry requires localization in cholesterol-rich domains
74. Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
75. Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover
76. 2 are structurally distinct from lipid rafts
77. Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D
78. The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate
79. Phosphoinositide lipids as signaling molecules: Common themes for signal transduction, cytoskeletal regulation, and membrane trafficking