Early Vλ diversification in sheep

Immunology

Volumn 103, Issue 1, 2001, Pages 26-34

  Jeong, Youngkee ^a,c   Osborne, Barbara A ^a   Goldsby, Richard A ^a,b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b AMHERST COLLEGE   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN;

ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; DNA LIBRARY; FETUS; GENE EXPRESSION; GENE REARRANGEMENT; GENE SEQUENCE; LYMPHOID TISSUE; MOLECULAR CLONING; NONHUMAN; PEYER PATCH; PREGNANCY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SHEEP; ANIMAL; ANTIBODY SPECIFICITY; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRENATAL DEVELOPMENT; SPLEEN;

ANIMALS; ANTIBODY DIVERSITY; BASE SEQUENCE; DNA, COMPLEMENTARY; EMBRYONIC AND FETAL DEVELOPMENT; FETUS; GENE REARRANGEMENT, B-LYMPHOCYTE, LIGHT CHAIN; IMMUNOGLOBULIN J-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; SHEEP; SPLEEN;

EID: 0034743993     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2001.01227.x     Document Type: Article

References (25)

1. Gerber HA, Morris B, Trevella W. The role of gut-associated lymphoid tissues in the generation of immunoglobulin-bearing lymphocytes in sheep. Aust J Exp Biol Med Sci 1986; 64:201-13.
2. Reynaud C-A, Mackay CR, Muller RG, Weill J-C. Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches. Cell 1991; 64:995-1005.
3. Reynaud C-A, Garcia C, Hein WR, Weill J-C. Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process. Cell 1995; 80:115-25.
4. Tuboly S, Glavits R, Bucsek M. Stages in the development of the ovine immune system. Zentralbl Veterinarmed [B] 1984; 31:81-95.
5. Miyasaka M, Morris B. The ontogeny of the lymphoid system and immune responsiveness in sheep. Prog Vet Microbiol Immun 1988; 4:21-55.
6. Symons DB, Binns RM. Immunoglobulin-bearing lymphocytes: their demonstration in adult sheep and ontogeny in the sheep fetus. Int Arch Allergy Appl Immunol 1975; 49:658-69.
7. Maddox JF, Mackay CR, Brandon MR. Ontogeny of ovine lymphocytes. II. An immunohistological study on the development of T lymphocytes in the sheep foetal spleen. Immunology 1987; 62:107-12.
8. Press CM, Halleraker M, Landsverk T. Ontogeny of leukocyte populations in the ileal Peyer's patch of sheep. Dev Comp Immunol 1992; 16:229-41.
9. Press CM, Hein WR, Landsverk T. Ontogeny of leukocyte populations in the spleen of foetal lambs with emphasis on the early prominence of B cells. Immunology 1993; 80:598-604.
10. Lucier MR, Thompson RE, Waire J, Lin AW, Osborne BA, Goldsby RA. Multiple sites of Vλ diversification in cattle. J Immunol 1998; 161:5438-44.
11. Foley RC, Beh KJ. Isolation and sequence of sheep Ig H and L chain cDNA. J Immunol 1989; 142:708-11.
12. Sinclair MC, Gilchrist J, Aitken R. Molecular characterization of bovine V lambda regions. J Immunol 1995; 155:3068-78.
13. Reynaud C-A, Dufour V, Weill J-C. Generation of diversity in mammalian gut-associated lymphoid tissues: Restriction V gene usage does not preclude complex V gene organization. J Immunol 1997; 159:3093-5.
14. Hein WR, Dudler L. Diversity of Ig light chain variable region gene expression in foetal lambs. Int Immunol 1998; 10:1251-9.
15. Maybaum TA, Reynolds JD. B cell selected for apoptosis in the sheep ileal Peyer's patch have enhanced mutational diversity in the Ig Vλ light chain. J Immunol 1996; 157:1474-84.
16. McCormack WT, Thompson CB. Somatic diversification of the chicken immunoglobulin light-chain gene. Adv Immunol 1990; 48:41-67.
17. Parng CL, Hansal S, Goldsby RA, Osborne BA. Mechanisms of immunoglobulin light chain diversification in cattle. J Immunol 1996; 157:5478-86.
18. Knight KL, Becker RS. Molecular basis of the allelic inheritance of rabbit immunoglobulin VH allotypes: implications for the generation of antibody diversity. Cell 1990; 60:963-70.
19. Ignatovich O, Tomlinson IM, Jones PT, Winter G. The creation of diversity in the human immunoglobulin Vλ repertoire. J Mol Biol 1997; 268:69-77.
20. Lawler AM, Kearney JF, Kuehl M, Gearhart PJ. Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus. Proc Natl Acad Sci USA 1989; 86:6744-8.
21. Kabat EA, Wu TT, Perry HM, Gottesman KS, Foeller C. Sequences of Proteins of Immunological Interest, 5th edn. Bethesda, MD: National Institutes of Health, 1991.
22. Victor KD, Capra JD. An apparently common mechanism of generating antibody diversity: length variation of the VL-JL junction. Mol Immunol 1994; 31:39-46.
23. Heidmann O, Rougeon F. Immunoglobulin kappa light-chain diversity in rabbit is based on the 3′ length heterogeneity of germline variable genes. Nature 1984; 311:74-6.
24. Berens SJ, Wylie DE, Lopez OJ. Use of a single VH family and long CDR3s in the variable region of cattle Ig heavy chains. Int Immunol 1997; 9:189-99.
25. H family and long CDR3s are the target for hypermutation in bovine immunoglobulin heavy chains. Immunol Rev 1998; 162:55-66.