In vitro metabolism of 14C-moxidectin by hepatic microsomes from various species

Veterinary Research Communications

Volumn 25, Issue 5, 2001, Pages 345-354

  Dupuy, J ^a   Escudero, E ^b   Eeckhoutte, C ^a   Sutra, J F ^a   Galtier, P ^a   Alvinerie, M ^a  

^a CEMAGREF   (France)

^b Campus de Espinardo   (Spain)

Author keywords

Avermectin; Cow; Cytochrome P450; Deer; Goat; Inhibitors; Liver; Metabolites; Microsomes; Pig; Rabbit; Rat

Indexed keywords

ALPHA NAPHTHOFLAVONE; ALPHA-NAPHTHOFLAVONE; ANTIINFECTIVE AGENT; ANTINEMATODAL AGENT; BENZOFLAVONE DERIVATIVE; CARBON; CLOTRIMAZOLE; ENZYME INHIBITOR; MACROLIDE; METYRAPONE; MILBEMYCIN; PESTICIDE; PIPERONYL BUTOXIDE; TOPICAL ANTIINFECTIVE AGENT; CARBON 14; CYTOCHROME P450 3A; CYTOCHROME P450 INHIBITOR; FLAVONE DERIVATIVE; MOXIDECTIN; NAPHTHOFLAVONE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CATTLE; COMPARATIVE STUDY; DEER; FEMALE; LIVER MICROSOME; MALE; METABOLISM; RABBIT; RANDOMIZATION; RAT; SHEEP; SPRAGUE DAWLEY RAT; SWINE; ANIMAL DISEASE; ANIMAL EXPERIMENT; CATTLE DISEASE; COW; DRUG DETERMINATION; DRUG INDICATION; DRUG METABOLISM; GOAT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; NONHUMAN; QUANTITATIVE ASSAY; SHEEP DISEASE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS, LOCAL; ANTINEMATODAL AGENTS; BENZOFLAVONES; CARBON RADIOISOTOPES; CATTLE; CLOTRIMAZOLE; DEER; ENZYME INHIBITORS; FEMALE; MACROLIDES; MALE; METYRAPONE; MICROSOMES, LIVER; PESTICIDE SYNERGISTS; PIPERONYL BUTOXIDE; RABBITS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SHEEP; SWINE;

EID: 0034743517     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010686508307     Document Type: Article

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