Central inhibition of AT1 receptors by eprosartan - In vitro autoradiography in the brain

Pharmacological Research

Volumn 43, Issue 3, 2001, Pages 251-255

  Muders, Frank ^a   Palkovits, Miklos ^b   Bahner, Udo ^a   Kirst, Ingrid ^a   Elsner, Dietmar ^a   Jandeleit Dahm, Karin ^c  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c AUSTIN HEALTH   (Australia)

Author keywords

Angiotensin II; Autoradiography; Brain nuclei; Rat

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; EPROSARTAN; IODINE 124; ACRYLIC ACID DERIVATIVE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; ANTIHYPERTENSIVE AGENT; IMIDAZOLE DERIVATIVE; RENIN; THIOPHENE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; BRAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG PENETRATION; DRUG RECEPTOR BINDING; HEMODYNAMICS; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PHARMACOLOGICAL BLOCKING; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECEPTOR BLOCKING; SUBFORNICAL ORGAN; THALAMUS MIDLINE NUCLEUS; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; BLOOD PRESSURE; BODY WEIGHT; DRUG ANTAGONISM; DRUG EFFECT; HEART RATE; METABOLISM; RADIOGRAPHY; WISTAR RAT;

ACRYLATES; ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; AUTORADIOGRAPHY; BLOOD PRESSURE; BLOOD-BRAIN BARRIER; BODY WEIGHT; BRAIN; HEART RATE; IMIDAZOLES; MALE; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; RENIN; THIOPHENES;

EID: 0034743478     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0767     Document Type: Article

References (28)

1. Localization and characterization of angiotensin II receptor binding and angiotensin converting enzyme in the human medulla oblongata
2. Brain angiotensin: Pathways and pharmacology
3. The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking and vasopressin responses to central angiotensin
4. Brain and pituitary angiotensin
5. Anxiolytic-like action of Dup753, a non-peptide angiotensin Ii receptor antagonist
6. Losartan influences behavioural effects of angiotensin II(3-7) in rats
7. Functions of angiotensin in the central nervous system
8. Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: A functional neuroanatomical review
9. Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functions
10. Central angiotensin II AT1-receptor antagonism in normal and heart-failed sheep
11. Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: Relationship to differences in prejunctional angiotensin II receptor blockade
12. Validation in awake rats of a tail-cuff method for measuring systolic pressure
13. Access of peripherally administered DuP 753 to rat brain angiotensin II receptors
14. Comparative expression of vasopressin and angiotensin type-1 receptor mRNA in rat hypothalamic nuclei: A double in situ hybridization study
15. The efferent projections of the subfornical organ of the rat: A circumventricular organ within a neural network subserving water balance
16. Angiotensin II immunoreactivity in the neural afferents and efferents of the subfornical organ of the rat
17. Subfornical organ efferents to neural systems for control of body water
18. Role for the subfornical organ in vasopressin release
19. The role of the subfornical organ in the salt and water balance
20. The circumventricular organs and the central actions of angiotensin
21. Circumventricular organs: Neuroendocrine interfaces between the brain and the hemal milieu
22. Distribution of angiotensin II receptor subtypes in rat brain nuclei
23. Microinjections of angiotensin II into the supraoptic and paraventricular nuclei produce potent antidiureses by vasopressin release mediated through adrenergic and angiotensin receptors
24. Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release
25. Angiotensin stimulation of vasopressin release from the rat hypothalamo-neurohypophyseal system in organ culture
26. Angiotensin II evokes noradrenaline release from the paraventricular nucleus in conscious rats
27. The role of angiotensin II in the regulation of ACTH secretion
28. Blockade by intravenous losartan of AT1 angiotensin II receptors in rat brain, kidney and adrenals demonstrated by in vitro autoradiography