Heat treatment of armphotericin B modifies its serum pharmacokinetics, tissue distribution, and renal toxicity following administration of a single intravenous dose to rabbits

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 7, 2001, Pages 2060-2063

  Kwong, E H ^a   Ramaswamy, M ^a   Bauer, E A ^a   Hartsel, S C ^a   Wasan, K M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; CREATININE; AMPHOTERICIN B; ANTIFUNGAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SAFETY; DRUG TISSUE LEVEL; FEMALE; HEART; HEATING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; LIVER; LUNG; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; SPLEEN; TIME; ANIMAL; BLOOD; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; TISSUE DISTRIBUTION;

AMPHOTERICIN B; ANIMALS; ANTIBIOTICS, ANTIFUNGAL; AREA UNDER CURVE; FEMALE; INJECTIONS, INTRAVENOUS; KIDNEY; RABBITS; TISSUE DISTRIBUTION;

EID: 0034743464     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.7.2060-2063.2001     Document Type: Article

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