Kinetics of testosterone 6β-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome P450 oxidoreductase and cytochrome b5 to human liver microsomes

Research Communications in Molecular Pathology and Pharmacology

Volumn 109, Issue 1-2, 2001, Pages 53-63

  Taguchi, M ^a   Imaoka, S ^a   Yoshii, K ^a   Kobayashi, K ^a   Hosokawa, M ^a   Shimada, N ^a   Funae, F ^a   Chiba, K ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME B5; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; CYTOCHROME P450 REDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TESTOSTERONE; CYP2C13 PROTEIN, RAT; CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; MIXED FUNCTION OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ARTICLE; BINDING AFFINITY; BIOTRANSFORMATION; CONTROLLED STUDY; DRUG METABOLISM; ENZYME MECHANISM; HORMONE METABOLISM; HYDROXYLATION; KINETICS; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; VELOCITY; ENZYMOLOGY; ESCHERICHIA COLI; HUMAN; IN VITRO STUDY; ISOLATION AND PURIFICATION; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS;

CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; HUMANS; KINETICS; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE;

EID: 0034743310     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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