A review of the applications of imiquimoid: A novel immune response modifier

Expert Opinion on Pharmacotherapy

Volumn 2, Issue 5, 2001, Pages 877-882

  Syed, T A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Creams; Cytokines; Imiquimod; Immune response modifier; Interleukins; Non nucleoside

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMIQUIMOD; IMMUNOMODULATING AGENT; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE CHEMOTACTIC FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; WATER; WATER OIL CREAM; AMINOQUINOLINE DERIVATIVE; IMMUNOLOGICAL ADJUVANT;

ANTIVIRAL ACTIVITY; ARTICLE; BASAL CELL CARCINOMA; CLINICAL TRIAL; CONDYLOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG FORMULATION; DRUG MECHANISM; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; EDEMA; EROSION; ERYTHEMA; GENITAL HERPES; HUMAN; IMMUNOMODULATION; MOLLUSCUM CONTAGIOSUM; PAIN; PRURITUS; PSORIASIS; SKIN DISEASE; ANIMAL; BIOSYNTHESIS; DRUG COST; REVIEW;

ADJUVANTS, IMMUNOLOGIC; AMINOQUINOLINES; ANIMALS; CYTOKINES; DRUG COSTS; HUMANS;

EID: 0034741974     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.2.5.877     Document Type: Article

References (37)

1. Induction of interferon and other cytokines by imiquimod and its hydroxylated metabolite R-842 in human blood cells in vitro
2. Cytokine induction and modifying the immune response to human papilloma virus with imiquimod
3. Imiquimod applied topically: A novel immune response modifier and a new class of drug
4. Development of a topically active imiquimod formulation
5. Immunomodulating and antiviral activities of the imidazoquinoline S-28463
6. Immunomodulating activities of imiquimod and its analogs, S-27609 and S-28463 in human keratinocyte and fibroblast cultures and mouse skin
7. Topical imiquimod. A review of its use in genital warts
8. Imiquimod: In vivo and in vitro characteristics and toxicology
9. Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463
10. Imiquimod, a novel topical immune response modifier induces migration of Langerhans' cells
11. Cytokine induction in mice by the immunomodulator imiquimod
12. The immune response modifier imiquimod requires STAT-1 for induction of interferon, interferon-stimulated genes and interleukin-6
13. Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609
14. Cytokine induction by the immunomodulators imiquimod and S-27609
15. Pharmacokinetics. Pharmacokinetic factors affecting epidermal penetration and percutaneous adsorption
16. 14C] imiquimod from a single application of cream
17. Imiquimod 5% cream (Aldara)
18. Imiquimod: An immune response modifier
19. Immunomodulatory and pharmacologic properties of imiquimod
20. Human papillomavirus infections: Epidiomology, pathogenesis and therapy
21. Self-administered topical 5% imiquimod cream for external anogenital warts
22. Treatment of genital warts with immune response modifier (imiquimod)
23. Imiquimod, a patient-applied immune response modifier for treatment of external genital warts
24. Management of female genital warts with an analog of imiquimod 2% in cream: A randomized, double-blind, placebo-controlled study
25. Treatment of external genital warts in men with imiquimod 2% in cream. A placebo-controlled, double-blind study
26. Treatment of molluscum contagiosum in males with an analog of imiquimod 1% in cream: A placebo-controlled, double-blind study
27. Topical imiquimod therapy for chronic giant molluscum contagiosum in a patient with advanced human immunodeficiency virus 1 disease
28. Treatment of genital herpes in males with imiquimod 1% cream: A randomized, double-blind, placebo-controlled study
29. Therapeutic response of basal cell carcinoma to the immune response modifier imiquimod 5% cream
30. Imiquimod: A novel treatment for lentigo maligna
31. Topical imiquimod treatment of a cutaneous melanoma metastasis
32. Immunomodulatory therapy in the management of viral infections in patients with HIV infection
33. Imiquimod cream for genital warts
34. 1998 Guidelines for treatment of sexually transmitted diseases
35. Imiquimod in clinical practice
36. Management of psoriasis vulgaris with 5% imiquimod cream
37. The cost effectiveness of patient-applied versus provider-administered intervention strategies for the treatment of external genital warts