[11C]Raclopride binding was reduced in vivo by sigma1 receptor ligand SA4503 in the mouse brain, while [11C]SA4503 binding was not by raclopride

Nuclear Medicine and Biology

Volumn 28, Issue 7, 2001, Pages 787-792

  Ishiwata, Kiichi ^a   Kobayashi, Tadayuki ^b   Kawamura, Kazunori ^a,c   Matsuno, Kiyoshi ^b   Senda, Michio ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b SANTEN PHARMACEUTICAL CO LTD   (Japan)

^c 141 0032   (Japan)

Author keywords

11C Raclopride; 11C SA4503; Dopamine D2 like receptor; PET; Sigma1 receptor

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE; 1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE C 11; 2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; BLOCKING AGENT; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER INHIBITOR; LIGAND; RACLOPRIDE; RACLOPRIDE C 11; RECEPTOR SUBTYPE; SA 6298; SIGMA 1 OPIATE RECEPTOR; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG; VANOXERINE; 2 CARBOMETHOXY 8 (3 FLUOROPROPYL) 3 (4 IODOPHENYL)TROPANE; 2-CARBOMETHOXY-8-(3-FLUOROPROPYL)-3-(4-IODOPHENYL)TROPANE; CARBON; CARRIER PROTEIN; DIAGNOSTIC AGENT; DOPAMINE TRANSPORTER; MEMBRANE PROTEIN; NERVE PROTEIN; PIPERAZINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; SIGMA 2 OPIATE RECEPTOR; SIGMA-1 RECEPTOR; SIGMA-2 RECEPTOR; TROPANE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DRUG ACTIVITY; DRUG BINDING; DRUG UPTAKE; IC 50; MALE; MOUSE; NONHUMAN; ANIMAL; BRAIN CIRCULATION; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; NEOSTRIATUM;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; CEREBROVASCULAR CIRCULATION; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; LIGANDS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; NEOSTRIATUM; NERVE TISSUE PROTEINS; PIPERAZINES; RACLOPRIDE; RADIOPHARMACEUTICALS; RECEPTORS, DOPAMINE D2; RECEPTORS, SIGMA; TROPANES;

EID: 0034741136     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(01)00238-4     Document Type: Article

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