Cloning and cellular localization of the canine progesterone receptor: Co-localization with growth hormone in the mammary gland

Journal of Steroid Biochemistry and Molecular Biology

Volumn 75, Issue 4-5, 2000, Pages 219-228

  Lantinga van Leeuwen, Irma S ^a   Van Garderen, Evert ^b   Rutteman, Gerard R ^a   Mol, Jan A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Autocrine; Carcinogenesis; Growth hormone; Paracrine; Progesterone receptor

Indexed keywords

AMINO ACID; GESTAGEN; GROWTH HORMONE; PROGESTERONE RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CELLULAR DISTRIBUTION; CODON; DOG; EPITHELIUM CELL; FEMALE; GENETIC CODE; HORMONE RECEPTOR INTERACTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALIGNANT TRANSFORMATION; MAMMARY GLAND; NONHUMAN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TISSUE DIFFERENTIATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; DOG DISEASES; DOGS; FEMALE; GROWTH HORMONE; IMMUNOHISTOCHEMISTRY; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MOLECULAR SEQUENCE DATA; RECEPTORS, PROGESTERONE;

CANIS FAMILIARIS;

EID: 0034739773     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00173-4     Document Type: Article

References (40)

1. Progestin regulation of cellular proliferation
2. Physiological action of progesterone in target tissues
3. The steroid and thyroid hormone receptor superfamily
4. Steroid receptor family: Structure and functions
5. The structure of the nuclear hormone receptors
6. Steroid receptor isoforms: Exception or rule?
7. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities
8. Mammary gland development is mediated by both stromal and epithelial progesterone receptors
9. Roles of estrogen and progesterone in normal mammary gland development, insights from progesterone receptor null mutant mice and in situ localization of receptor
10. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands
11. Progestagens and mammary gland development: Differentiation versus carcinogenesis
12. Progestin-induced growth hormone excess in the dog originates in the mammary gland
13. Growth hormone mRNA in mammary gland tumors of dogs and cats
14. New insights in the molecular mechanism of progestin-induced proliferation of mammary epithelium; induction of the local biosynthesis of growth hormone (GH) in the mammary gland of dogs, cats and humans
15. Expression of growth hormone in canine mammary tissue and mammary tumors. Evidence for a potential autocrine/paracrine stimulatory loop
16. Expression of the gene encoding growth hormone in the human mammary gland
17. Canine mammary growth hormone gene transcription initiates at the pituitary specific start site in the absence of Pit-1
18. Construction and characterization of an eight fold redundant dog genomic bacterial artificial chromosome library
19. Genetic mapping of the copper toxicosis locus in Bedlington terriers to dog chromosome 10, in a region syntenic to human chromosome region 2p13-16
20. Prolactin binding in benign and malignant mammary tissue of female dogs
21. Monoclonal antibodies to human progesterone receptor: Characterization by biochemical and immunohistochemical techniques
22. Murine progesterone receptor exists predominantly as the 83-kDa 'A' form
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
25. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA
26. Cloning and sequence analysis of rabbit-progesterone-receptor complementary DNA
27. The chicken progesterone receptor: Sequence, expression and functional analysis
28. Molecular cloning, sequence analyses, and expression of complementary DNA encoding murine progesterone receptor
29. Characterization of multiple mRNAs originating from the chicken progesterone receptor gene
30. Synthesis of human progesterone receptors in T47D cells. Nascent A- and B-receptors are active without a phosphorylation-dependent post-translational maturation step
31. Characterization of progesterone receptor A and B expression in human breast cancer
32. Immunohistochemical localization of oestrogen and progesterone receptors in the uterus of the normal bitch during oestrus and metoestrus
33. Use of PRKO mice to study the role of progesterone in mammary gland development
34. Oestrogen (ER) and progestin receptors (PR) in mammary tissue of the female dog: Different receptor profile in non-malignant and malignant states
35. The loss of estrogen and progesterone receptor gene expression in human breast cancer
36. Immunohistochemistry with keratin, vimentin, desmin, and α-smooth muscle actin monoclonal antibodies in canine mammary gland: Benign mammary tumours and duct ectasias
37. Immunohistochemical study of androgen receptors in metastatic prostate cancer. Comparison of receptor content and response to hormonal therapy
38. Image analysis of androgen receptor immunostaining in prostate cancer accurately predicts response to hormonal therapy
39. Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas
40. GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours