Synergistic cooperation between water-soluble chitosan oligomers and interferon-γ for induction of nitric oxide synthesis and tumoricidal activity in murine peritoneal macrophages

Cancer Letters

Volumn 159, Issue 2, 2000, Pages 189-195

  Seo, Won Gil ^a,b   Pae, Hyun Ock ^a,b   Kim, Na Young ^b   Oh, Gi Su ^b   Park, In Sik ^b   Kim, Yoo Hyun ^b   Kim, Young Myeong ^b   Lee, Young Haeng ^b   Jun, Chang Duk ^a   Chung, Hun Taeg ^a,b  

^a Wonkwang University School of Medicine   (South Korea)

^b 570 749   (South Korea)

Author keywords

Chitosan oligomers; Macrophages; Nitric oxide; Tumor necrosis factor ; Tumoricidal activity

Indexed keywords

CHITOSAN; CYTOKINE; GAMMA INTERFERON; NITRIC OXIDE; OLIGOMER;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL KILLING; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DRUG POTENTIATION; DRUG SOLUBILITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; TUMOR CELL;

ANIMAL; ANTIBODIES, MONOCLONAL; CHITIN; CULTURE MEDIA, CONDITIONED; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; INTERFERON TYPE II; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; SOLUBILITY; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR;

EID: 0034739705     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00551-6     Document Type: Article

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