Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene

Toxicology Letters

Volumn 117, Issue 1-2, 2000, Pages 69-77

  Chen, Ruei Ming ^a,c   Chou, Ming W ^b   Ueng, Tzuu Huei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

6 Nitrochrysene; Cytochrome P450 1A1; HepG2 cells; Induction

Indexed keywords

6 NITROCHRYSENE; CYP1A1; CYTOCHROME P450; MESSENGER RNA; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER METABOLISM; METABOLIC ACTIVATION; PRIORITY JOURNAL; TOXICITY TESTING; TRANSCRIPTION REGULATION; XENOBIOTIC METABOLISM;

BENZOPYRENE HYDROXYLASE; CARCINOMA, HEPATOCELLULAR; CHRYSENES; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMAN; METHYLCHOLANTHRENE; MICROSOMES; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0034734834     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(00)00242-3     Document Type: Article

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