Molecular characteristics of the inhibition of human neutrophil elastase by nonsteroidal antiinflammatory drugs

Experimental and Molecular Medicine

Volumn 32, Issue 3, 2000, Pages 146-154

  Kang, Kooil ^a   Bae, Sung Jun ^a   Kim, Woo Mi ^a   Lee, Dae Heui ^a   Cho, Unsuck ^a   Lee, Myung Huck ^a   Lee, Mu Sang ^b   Nam, Sang Il ^b   Kuettner, Klaus E ^c   Schwartz, David E ^c  

^a Kosin University   (South Korea)

^b Kyungpook National University   (South Korea)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Human neutrophil elastase; Inflammatory diseases; NSAIDs; Raman shifts

Indexed keywords

ACETYLSALICYLIC ACID; IBUPROFEN; KETOPROFEN; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OXYPHENBUTAZONE; PHENYLBUTAZONE; SALICYLIC ACID; TOLMETIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PURIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFLAMMATION; ION EXCHANGE CHROMATOGRAPHY; RAMAN SPECTROMETRY;

EID: 0034734657     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2000.25     Document Type: Article

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